ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSMQIEIKDG RSDNSPLPER KLVTLIQESY DSLKDDNEIN LSTESTSNLL IKLVLEKLEK 

        70         80         90        100        110        120 
HSSLYKYIAS VTTLNIEGLN EENANFSLKN DIGASWESKK DGIFNYKLED KNNNECYLIT 


ILWLHK 

References and documentation are available.

Number of amino acids: 126

Molecular weight: 14498.36

Theoretical pI: 4.93

Amino acid composition: 
Ala (A)   3	  2.4%
Arg (R)   2	  1.6%
Asn (N)  13	 10.3%
Asp (D)   8	  6.3%
Cys (C)   1	  0.8%
Gln (Q)   2	  1.6%
Glu (E)  13	 10.3%
Gly (G)   4	  3.2%
His (H)   2	  1.6%
Ile (I)  11	  8.7%
Leu (L)  18	 14.3%
Lys (K)  13	 10.3%
Met (M)   2	  1.6%
Phe (F)   2	  1.6%
Pro (P)   2	  1.6%
Ser (S)  14	 11.1%
Thr (T)   6	  4.8%
Trp (W)   2	  1.6%
Tyr (Y)   5	  4.0%
Val (V)   3	  2.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 15

Atomic composition:

Carbon      C	       641
Hydrogen    H	      1026
Nitrogen    N	       166
Oxygen      O	       209
Sulfur      S	         3

Formula: C641H1026N166O209S3
Total number of atoms: 2045

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    18450
Abs 0.1% (=1 g/l)   1.273, assuming all pairs of Cys residues form cystines


Ext. coefficient    18450
Abs 0.1% (=1 g/l)   1.273, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.71
This classifies the protein as unstable.



Aliphatic index: 99.05

Grand average of hydropathicity (GRAVY): -0.578