ProtParam
User-provided sequence:
10 20 30 40 50 60
MSMSSTVIKF RAGVCEYNED SRLCTPIPVQ GEIEIKPNEE EELGFWDFEW RPTEKPVGRE
70 80 90 100 110 120
LDPISLILIP GETMWVPIKS SKSGRIFALV FSSNERYFFW LQEKNSGNLP LNELSAKDKE
130 140 150
IYNKMIGVLN NSSESDEEES NDEKQKAQDV DVSMQD
References and
documentation are available.
Number of amino acids: 156
Molecular weight: 17902.06
Theoretical pI: 4.46
Total number of negatively charged residues (Asp + Glu): 30
Total number of positively charged residues (Arg + Lys): 17
Atomic composition:
Carbon C 790
Hydrogen H 1226
Nitrogen N 204
Oxygen O 256
Sulfur S 7
Formula: C
790H
1226N
204O
256S
7
Total number of atoms: 2483
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 26595
Abs 0.1% (=1 g/l) 1.486, assuming all pairs of Cys residues form cystines
Ext. coefficient 26470
Abs 0.1% (=1 g/l) 1.479, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 57.84
This classifies the protein as unstable.
Aliphatic index: 74.29
Grand average of hydropathicity (GRAVY): -0.631