ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSNQALYEKL EQTRTILSVK LAELINMTTI ADRNDDDEGS FAQENSELAV ATTSVMMVNN 

        70         80         90        100        110        120 
QTMQLIKNVQ DLLILTRSIK EKWLLNQIPV TEHSKVTRFD EKQIEELLDN CIETFVAEKT 


T 

References and documentation are available.

Number of amino acids: 121

Molecular weight: 13862.78

Theoretical pI: 4.60

Amino acid composition: 
Ala (A)   7	  5.8%
Arg (R)   4	  3.3%
Asn (N)   9	  7.4%
Asp (D)   7	  5.8%
Cys (C)   1	  0.8%
Gln (Q)   8	  6.6%
Glu (E)  13	 10.7%
Gly (G)   1	  0.8%
His (H)   1	  0.8%
Ile (I)   9	  7.4%
Leu (L)  14	 11.6%
Lys (K)   8	  6.6%
Met (M)   5	  4.1%
Phe (F)   3	  2.5%
Pro (P)   1	  0.8%
Ser (S)   7	  5.8%
Thr (T)  13	 10.7%
Trp (W)   1	  0.8%
Tyr (Y)   1	  0.8%
Val (V)   8	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 12

Atomic composition:

Carbon      C	       601
Hydrogen    H	       989
Nitrogen    N	       161
Oxygen      O	       200
Sulfur      S	         6

Formula: C601H989N161O200S6
Total number of atoms: 1957

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     6990
Abs 0.1% (=1 g/l)   0.504, assuming all pairs of Cys residues form cystines


Ext. coefficient     6990
Abs 0.1% (=1 g/l)   0.504, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.74
This classifies the protein as stable.



Aliphatic index: 99.09

Grand average of hydropathicity (GRAVY): -0.335