ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSNSLEERLR ANSSAFDGLL ALIPAKYYYD EKSQEQWKAK KKTKEQSKND KLKKLDPEQR 

        70         80         90        100        110        120 
DDETSSTLEV MKKKEKDAKP VVLPGEKFKH MKMQKQKEAT SKVEGDSDLN VEVNDPMIIA 

       130        140        150        160        170        180 
PDEDEEEEED IKVIFDDEGN EIPLESKKDT TEPDRSVEKK SITEEEKLQR KKNLEALRSK 

       190        200        210        220        230        240 
LQAKISDMKS KRKAPGSREA ILAQRKRKEE LKKRKRLESE QEQDQDEIAS DSDMEDIDSD 

       250        260        270        280        290        300 
LENNSKKRFK KGKKDSEINA DGVMFQNIIF DDGARATSDL QRLRKAGRTK GPAKNDVKSH 

       310        320        330        340        350        360 
LKLLEAKKNK MEAKDELEQI KQKEKEKWQK AMLQAEGIKI RDDEKLLRKA IKRKEAQKRK 

       370        380        390        400        410        420 
SAIEWSERKR VVEDTISERQ KRREENLRIR KDNKGKKRNK QEKMKRKYVG SAVPKKRAGF 

       430 
EGRLKTGKKK GGPK 

References and documentation are available.

Number of amino acids: 434

Molecular weight: 50481.52

Theoretical pI: 9.57

Amino acid composition: 
Ala (A)  28	  6.5%
Arg (R)  32	  7.4%
Asn (N)  16	  3.7%
Asp (D)  36	  8.3%
Cys (C)   0	  0.0%
Gln (Q)  21	  4.8%
Glu (E)  55	 12.7%
Gly (G)  18	  4.1%
His (H)   2	  0.5%
Ile (I)  21	  4.8%
Leu (L)  30	  6.9%
Lys (K)  84	 19.4%
Met (M)  11	  2.5%
Phe (F)   7	  1.6%
Pro (P)  12	  2.8%
Ser (S)  29	  6.7%
Thr (T)  11	  2.5%
Trp (W)   3	  0.7%
Tyr (Y)   4	  0.9%
Val (V)  14	  3.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 91
Total number of positively charged residues (Arg + Lys): 116

Atomic composition:

Carbon      C	      2170
Hydrogen    H	      3652
Nitrogen    N	       658
Oxygen      O	       698
Sulfur      S	        11

Formula: C2170H3652N658O698S11
Total number of atoms: 7189

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    22460
Abs 0.1% (=1 g/l)   0.445

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 56.95
This classifies the protein as unstable.



Aliphatic index: 61.64

Grand average of hydropathicity (GRAVY): -1.459