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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSPFGSKKNR SLSVRVSTFD SELEFKLEPR ASGQDLFDLV CRTIGLRESW YFGLQYVDTR

70 80 90 100 110 120
SNVSWLKMEK RVRDQRVELH ASNNVYVFSF YAKFFPENVS EELIQEITQH LFFLQVKQSI

130 140 150 160 170 180
LSMDIYCRPE ASVLLASYAV HVQYGPYDYE TYKDGMLAGG ELLPKGVTDQ YQMTPEMWEE

190 200 210 220 230 240
RIKTWYMDHE PMTRDEVEME YLKIAQDLDM YGVNYFPITN KNKTKLWLGV TSVGLNIYDE

250 260 270 280 290 300
RDKLTPKTTF QWNEIRHVSF DDKKFTIRLV DAKVSNFIFY SQDLHINKMI LDLCKGNHDL

310 320 330 340 350 360
YMRRRKPDTM EIQQMKAQAK EEKQRRQIER KKFIREKKLR EKAEHERYEL EKSMEHLQNE

370 380 390 400 410 420
MRMANDALRR SEETKELYFE KSRVNEEQMQ LTECKANHFK TEMDRLRERQ MKIEREKHDL

430 440 450 460 470 480
EKKIRDADFY VHQLTVENDK REAETEKLRK ELICAKMAER EATARLLEFL NSGRKSSTDS

490 500 510 520 530 540
LLTASSVSHA ANTASSMAAI STPSLITSSS TNDLETAGGA ELTTHSSHYL VQGDNSSGIS

550 560 570 580 590 600
DDFEPKEFIL TDNEMEQITN EMERNHLDYL RNSKQVQSQL QTLRSEIAPH KIEENQSNLD

610 620 630
ILSEAQIKAG ENKYSTLKKL KSGSTKARVA FFEEL


References and documentation are available.

Number of amino acids: 635 Molecular weight: 74492.25 Theoretical pI: 6.03
Amino acid composition: 
Ala (A) 34 5.4% Arg (R) 42 6.6% Asn (N) 29 4.6% Asp (D) 36 5.7% Cys (C) 5 0.8% Gln (Q) 31 4.9% Glu (E) 69 10.9% Gly (G) 20 3.1% His (H) 17 2.7% Ile (I) 29 4.6% Leu (L) 59 9.3% Lys (K) 53 8.3% Met (M) 24 3.8% Phe (F) 26 4.1% Pro (P) 14 2.2% Ser (S) 51 8.0% Thr (T) 37 5.8% Trp (W) 6 0.9% Tyr (Y) 24 3.8% Val (V) 29 4.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 105 Total number of positively charged residues (Arg + Lys): 95 Atomic composition: Carbon C 3269 Hydrogen H 5168 Nitrogen N 914 Oxygen O 1018 Sulfur S 29 Formula: C3269H5168N914O1018S29 Total number of atoms: 10398 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 69010 Abs 0.1% (=1 g/l) 0.926, assuming all pairs of Cys residues form cystines Ext. coefficient 68760 Abs 0.1% (=1 g/l) 0.923, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.59 This classifies the protein as unstable. Aliphatic index: 72.65 Grand average of hydropathicity (GRAVY): -0.776