ProtParam
User-provided sequence:
10 20 30 40 50 60
MSQESSVLSE SQEQLANNPK IEDTSPPSAN SRDNSKPVLP WDYKNKAIEI KSFSGYKVNF
70 80 90 100 110
TGWIRRDVRE ERQRGSEFTA SDVKGSDDKA TRKKEPADED PEVKQLEKEG EDGLDS
References and
documentation are available.
Number of amino acids: 116
Molecular weight: 13092.21
Theoretical pI: 4.80
Total number of negatively charged residues (Asp + Glu): 25
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 559
Hydrogen H 886
Nitrogen N 162
Oxygen O 199
Sulfur S 1
Formula: C
559H
886N
162O
199S
1
Total number of atoms: 1807
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 13980
Abs 0.1% (=1 g/l) 1.068
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 66.17
This classifies the protein as unstable.
Aliphatic index: 50.43
Grand average of hydropathicity (GRAVY): -1.326