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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQESSVLSE SQEQLANNPK IEDTSPPSAN SRDNSKPVLP WDYKNKAIEI KSFSGYKVNF

70 80 90 100 110
TGWIRRDVRE ERQRGSEFTA SDVKGSDDKA TRKKEPADED PEVKQLEKEG EDGLDS


References and documentation are available.

Number of amino acids: 116 Molecular weight: 13092.21 Theoretical pI: 4.80
Amino acid composition: 
Ala (A) 6 5.2% Arg (R) 7 6.0% Asn (N) 6 5.2% Asp (D) 11 9.5% Cys (C) 0 0.0% Gln (Q) 5 4.3% Glu (E) 14 12.1% Gly (G) 6 5.2% His (H) 0 0.0% Ile (I) 4 3.4% Leu (L) 5 4.3% Lys (K) 12 10.3% Met (M) 1 0.9% Phe (F) 3 2.6% Pro (P) 7 6.0% Ser (S) 15 12.9% Thr (T) 4 3.4% Trp (W) 2 1.7% Tyr (Y) 2 1.7% Val (V) 6 5.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 25 Total number of positively charged residues (Arg + Lys): 19 Atomic composition: Carbon C 559 Hydrogen H 886 Nitrogen N 162 Oxygen O 199 Sulfur S 1 Formula: C559H886N162O199S1 Total number of atoms: 1807 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 13980 Abs 0.1% (=1 g/l) 1.068 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 66.17 This classifies the protein as unstable. Aliphatic index: 50.43 Grand average of hydropathicity (GRAVY): -1.326