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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQHLLLLIL LSLLLLHKPI SATTIIQKFK EAPQFYNSAD CPLIDDSESD DDVVAKPIFC

70 80 90 100 110 120
SRRAVHVAMT LDAAYIRGSV AAVLSVLQHS SCPENIVFHF VASASADASS LRATISSSFP

130 140 150 160 170 180
YLDFTVYVFN VSSVSRLISS SIRSALDCPL NYARSYLADL LPPCVRRVVY LDSDLILVDD

190 200 210 220 230 240
IAKLAATDLG RDSVLAAPEY CNANFTSYFT STFWSNPTLS LTFADRKACY FNTGVMVIDL

250 260 270 280 290 300
SRWREGAYTS RIEEWMAMQK RMRIYELGSL PPFLLVFAGL IKPVNHRWNQ HGLGGDNFRG

310 320 330 340 350
LCRDLHPGPV SLLHWSGKGK PWARLDAGRP CPLDALWAPY DLLQTPFALD S


References and documentation are available.

Number of amino acids: 351 Molecular weight: 39019.90 Theoretical pI: 6.49
Amino acid composition: 
Ala (A) 34 9.7% Arg (R) 21 6.0% Asn (N) 11 3.1% Asp (D) 25 7.1% Cys (C) 9 2.6% Gln (Q) 7 2.0% Glu (E) 8 2.3% Gly (G) 14 4.0% His (H) 9 2.6% Ile (I) 17 4.8% Leu (L) 47 13.4% Lys (K) 10 2.8% Met (M) 6 1.7% Phe (F) 17 4.8% Pro (P) 21 6.0% Ser (S) 38 10.8% Thr (T) 14 4.0% Trp (W) 7 2.0% Tyr (Y) 13 3.7% Val (V) 23 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 33 Total number of positively charged residues (Arg + Lys): 31 Atomic composition: Carbon C 1767 Hydrogen H 2737 Nitrogen N 467 Oxygen O 501 Sulfur S 15 Formula: C1767H2737N467O501S15 Total number of atoms: 5487 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 58370 Abs 0.1% (=1 g/l) 1.496, assuming all pairs of Cys residues form cystines Ext. coefficient 57870 Abs 0.1% (=1 g/l) 1.483, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.80 This classifies the protein as unstable. Aliphatic index: 99.80 Grand average of hydropathicity (GRAVY): 0.145