ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQKACYVCG KIGHLAEDCD SERLCYNCNK PGHVQTDCTM PRTVEFKQCY NCGETGHVRS 

        70         80         90        100        110        120 
ECTVQRCFNC NQTGHISREC PEPKKTSRFS KVSCYKCGGP NHMAKDCMKE DGISGLKCYT 

       130        140        150 
CGQAGHMSRD CQNDRLCYNC NETGHISKDC PKA 

References and documentation are available.

Number of amino acids: 153

Molecular weight: 17103.39

Theoretical pI: 8.19

Amino acid composition: 
Ala (A)   5	  3.3%
Arg (R)   8	  5.2%
Asn (N)   9	  5.9%
Asp (D)   8	  5.2%
Cys (C)  21	 13.7%
Gln (Q)   7	  4.6%
Glu (E)   9	  5.9%
Gly (G)  13	  8.5%
His (H)   7	  4.6%
Ile (I)   4	  2.6%
Leu (L)   4	  2.6%
Lys (K)  13	  8.5%
Met (M)   5	  3.3%
Phe (F)   3	  2.0%
Pro (P)   6	  3.9%
Ser (S)  10	  6.5%
Thr (T)   9	  5.9%
Trp (W)   0	  0.0%
Tyr (Y)   6	  3.9%
Val (V)   6	  3.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 21

Atomic composition:

Carbon      C	       700
Hydrogen    H	      1108
Nitrogen    N	       220
Oxygen      O	       229
Sulfur      S	        26

Formula: C700H1108N220O229S26
Total number of atoms: 2283

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10190
Abs 0.1% (=1 g/l)   0.596, assuming all pairs of Cys residues form cystines


Ext. coefficient     8940
Abs 0.1% (=1 g/l)   0.523, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 56.33
This classifies the protein as unstable.



Aliphatic index: 35.03

Grand average of hydropathicity (GRAVY): -0.808