ProtParam
User-provided sequence:
10 20 30 40 50 60
MSQNSNPAVV LEKVGDIAIE QRPIPTIKDP HYVKLAIKAT GICGSDIHYY RSGGIGKYIL
70 80 90 100 110 120
KAPMVLGHES SGQVVEVGDA VTRVKVGDRV AIEPGVPSRY SDETKEGSYN LCPHMAFAAT
130 140 150 160 170 180
PPIDGTLVKY YLSPEDFLVK LPEGVSYEEG ACVEPLSVGV HSNKLAGVRF GTKVVVFGAG
190 200 210 220 230 240
PVGLLTGAVA RAFGATDVIF VDVFDNKLQR AKDFGATNTF NSSQFSTDKA QDLADGVQKL
250 260 270 280 290 300
LGGNHADVVF ECSGADVCID AAVKTTKVGG TMVQVGMGKN YTNFPIAEVS GKEMKLIGCF
310 320 330 340 350
RYSFGDYRDA VNLVATGKVN VKPLITHKFK FEDAAKAYDY NIAHGGEVVK TIIFGPE
References and
documentation are available.
Number of amino acids: 357
Molecular weight: 38096.53
Theoretical pI: 6.26
Total number of negatively charged residues (Asp + Glu): 40
Total number of positively charged residues (Arg + Lys): 37
Atomic composition:
Carbon C 1708
Hydrogen H 2683
Nitrogen N 451
Oxygen O 511
Sulfur S 12
Formula: C
1708H
2683N
451O
511S
12
Total number of atoms: 5365
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 21235
Abs 0.1% (=1 g/l) 0.557, assuming all pairs of Cys residues form cystines
Ext. coefficient 20860
Abs 0.1% (=1 g/l) 0.548, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 25.86
This classifies the protein as stable.
Aliphatic index: 86.50
Grand average of hydropathicity (GRAVY): -0.015