ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQNVYIVST ARTPIGSFQG SLSSKTAVEL GAVALKGALA KVPELDASKD FDEIIFGNVL 

        70         80         90        100        110        120 
SANLGQAPAR QVALAAGLSN HIVASTVNKV CASAMKAIIL GAQSIKCGNA DVVVAGGCES 

       130        140        150        160        170        180 
MTNAPYYMPA ARAGAKFGQT VLVDGVERDG LNDAYDGLAM GVHAEKCARD WDITREQQDN 

       190        200        210        220        230        240 
FAIESYQKSQ KSQKEGKFDN EIVPVTIKGF RGKPDTQVTK DEEPARLHVE KLRSARTVFQ 

       250        260        270        280        290        300 
KENGTVTAAN ASPINDGAAA VILVSEKVLK EKNLKPLAII KGWGEAAHQP ADFTWAPSLA 

       310        320        330        340        350        360 
VPKALKHAGI EDINSVDYFE FNEAFSVVGL VNTKILKLDP SKVNVYGGAV ALGHPLGCSG 

       370        380        390 
ARVVVTLLSI LQQEGGKIGV AAICNGGGGA SSIVIEKI 

References and documentation are available.

Number of amino acids: 398

Molecular weight: 41728.69

Theoretical pI: 7.00

Amino acid composition: 
Ala (A)  53	 13.3%
Arg (R)  11	  2.8%
Asn (N)  19	  4.8%
Asp (D)  19	  4.8%
Cys (C)   6	  1.5%
Gln (Q)  16	  4.0%
Glu (E)  22	  5.5%
Gly (G)  38	  9.5%
His (H)   6	  1.5%
Ile (I)  25	  6.3%
Leu (L)  29	  7.3%
Lys (K)  30	  7.5%
Met (M)   5	  1.3%
Phe (F)  12	  3.0%
Pro (P)  15	  3.8%
Ser (S)  27	  6.8%
Thr (T)  16	  4.0%
Trp (W)   3	  0.8%
Tyr (Y)   7	  1.8%
Val (V)  39	  9.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1845
Hydrogen    H	      2979
Nitrogen    N	       511
Oxygen      O	       566
Sulfur      S	        11

Formula: C1845H2979N511O566S11
Total number of atoms: 5912

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    27305
Abs 0.1% (=1 g/l)   0.654, assuming all pairs of Cys residues form cystines


Ext. coefficient    26930
Abs 0.1% (=1 g/l)   0.645, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 28.73
This classifies the protein as stable.



Aliphatic index: 94.65

Grand average of hydropathicity (GRAVY): 0.011