Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQQDNVKAA AEGVANLHLD EATGEMVSKS ELKKRIKQRQ VEAKKAAKKA AAQPKPASKK

70 80 90 100 110 120
KTDLFADLDP SQYFETRSRQ IQELRKTHEP NPYPHKFHVS ISNPEFLAKY AHLKKGETLP

130 140 150 160 170 180
EEKVSIAGRI HAKRESGSKL KFYVLHGDGV EVQLMSQLQD YCDPDSYEKD HDLLKRGDIV

190 200 210 220 230 240
GVEGYVGRTQ PKKGGEGEVS VFVSRVQLLT PCLHMLPADH FGFKDQETRY RKRYLDLIMN

250 260 270 280 290 300
KDARNRFITR SEIIRYIRRF LDQRKFIEVE TPMMNVIAGG ATAKPFITHH NDLDMDMYMR

310 320 330 340 350 360
IAPELFLKQL VVGGLDRVYE IGRQFRNEGI DMTHNPEFTT CEFYQAYADV YDLMDMTELM

370 380 390 400 410 420
FSEMVKEITG SYIIKYHPDP ADPAKELELN FSRPWKRINM IEELEKVFNV KFPSGDQLHT

430 440 450 460 470 480
AETGEFLKKI LVDNKLECPP PLTNARMLDK LVGELEDTCI NPTFIFGHPQ MMSPLAKYSR

490 500 510 520 530 540
DQPGLCERFE VFVATKEICN AYTELNDPFD QRARFEEQAR QKDQGDDEAQ LVDETFCNAL

550 560 570 580 590
EYGLPPTGGW GCGIDRLAMF LTDSNTIREV LLFPTLKPDV LREEVKKEEE N


References and documentation are available.

Number of amino acids: 591 Molecular weight: 67958.55 Theoretical pI: 5.78
Amino acid composition: 
Ala (A) 37 6.3% Arg (R) 35 5.9% Asn (N) 21 3.6% Asp (D) 41 6.9% Cys (C) 9 1.5% Gln (Q) 26 4.4% Glu (E) 55 9.3% Gly (G) 33 5.6% His (H) 16 2.7% Ile (I) 28 4.7% Leu (L) 52 8.8% Lys (K) 48 8.1% Met (M) 20 3.4% Phe (F) 30 5.1% Pro (P) 33 5.6% Ser (S) 23 3.9% Thr (T) 29 4.9% Trp (W) 2 0.3% Tyr (Y) 20 3.4% Val (V) 33 5.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 96 Total number of positively charged residues (Arg + Lys): 83 Atomic composition: Carbon C 3018 Hydrogen H 4739 Nitrogen N 825 Oxygen O 903 Sulfur S 29 Formula: C3018H4739N825O903S29 Total number of atoms: 9514 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41300 Abs 0.1% (=1 g/l) 0.608, assuming all pairs of Cys residues form cystines Ext. coefficient 40800 Abs 0.1% (=1 g/l) 0.600, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.12 This classifies the protein as unstable. Aliphatic index: 75.25 Grand average of hydropathicity (GRAVY): -0.602