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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQRKRYSLN VVTSPSIPSP TPSAPIRTNE SNWEAASPAS AASSFLPNVH HGGTVLNPGL

70 80 90 100 110 120
GIMRSPSLNK SGAFGRSGSS GSSTVIEPSN IKLLLIGDAN VGKTAMILSY CRELLTRAEM

130 140 150 160 170 180
SRSARLRHQQ QQQHKDLGLK KTVVNHRLSM KEKRKRYSSN DFEKEFKDIN HFADETSDFG

190 200 210 220 230 240
NPNIGDDNNH EMADPNEIVI ETRSTIGIDI KTNLVNIDNR FFNVILWDTA GQERYQNAII

250 260 270 280 290 300
PSLYKKTNAV ILTYDITNAK SFQSCMERWI VQALENFSSQ DLLKARFFLV GNKIDLYKER

310 320 330 340 350 360
QVTHYDVVQM VQEMQLKHGI KISGNFEVSC KWVNVVERTM NMIILDLVEN GCFENNDPCV

370 380 390 400 410
SITTSDDVQG HEQEFHDTVE EPFNFTRQRQ HQLEKNNTVD ITKPNDDIAN NQSICCV


References and documentation are available.

Number of amino acids: 417 Molecular weight: 47116.01 Theoretical pI: 6.33
Amino acid composition: 
Ala (A) 20 4.8% Arg (R) 22 5.3% Asn (N) 37 8.9% Asp (D) 24 5.8% Cys (C) 7 1.7% Gln (Q) 21 5.0% Glu (E) 26 6.2% Gly (G) 20 4.8% His (H) 12 2.9% Ile (I) 30 7.2% Leu (L) 28 6.7% Lys (K) 24 5.8% Met (M) 11 2.6% Phe (F) 17 4.1% Pro (P) 16 3.8% Ser (S) 38 9.1% Thr (T) 24 5.8% Trp (W) 4 1.0% Tyr (Y) 8 1.9% Val (V) 28 6.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 50 Total number of positively charged residues (Arg + Lys): 46 Atomic composition: Carbon C 2050 Hydrogen H 3249 Nitrogen N 593 Oxygen O 646 Sulfur S 18 Formula: C2050H3249N593O646S18 Total number of atoms: 6556 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 34295 Abs 0.1% (=1 g/l) 0.728, assuming all pairs of Cys residues form cystines Ext. coefficient 33920 Abs 0.1% (=1 g/l) 0.720, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.62 This classifies the protein as unstable. Aliphatic index: 78.51 Grand average of hydropathicity (GRAVY): -0.534