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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQRSSQHIV GIHYAVGPKI GEGSFGVIFE GENILHSCQA QTGSKRDSSI IMANEPVAIK

70 80 90 100 110 120
FEPRHSDAPQ LRDEFRAYRI LNGCVGIPHA YYFGQEGMHN ILIIDLLGPS LEDLFEWCGR

130 140 150 160 170 180
KFSVKTTCMV AKQMIDRVRA IHDHDLIYRD IKPDNFLISQ YQRISPEGKV IKSCASSSNN

190 200 210 220 230 240
DPNLIYMVDF GMAKQYRDPR TKQHIPYRER KSLSGTARYM SINTHFGREQ SRRDDLESLG

250 260 270 280 290 300
HVFFYFLRGS LPWQGLKAPN NKLKYEKIGM TKQKLNPDDL LLNNAIPYQF ATYLKYARSL

310 320 330 340 350 360
KFDEDPDYDY LISLMDDALR LNDLKDDGHY DWMDLNGGKG WNIKINRRAN LHGYGNPNPR

370 380 390 400 410 420
VNGNTARNNV NTNSKTRNTT PVATPKQQAQ NSYNKDNSKS RISSNPQSFT KQQHVLKKIE

430 440 450 460 470 480
PNSKYIPETH SNLQRPIKSQ SQTYDSISHT QNSPFVPYSS SKANPKRSNN EHNLPNHYTN

490 500 510 520
LANKNINYQS QRNYEQENDA YSDDENDTFC SKIYKYCCCC FCCC


References and documentation are available.

Number of amino acids: 524 Molecular weight: 60260.61 Theoretical pI: 8.97
Amino acid composition: 
Ala (A) 24 4.6% Arg (R) 31 5.9% Asn (N) 47 9.0% Asp (D) 34 6.5% Cys (C) 13 2.5% Gln (Q) 28 5.3% Glu (E) 21 4.0% Gly (G) 28 5.3% His (H) 18 3.4% Ile (I) 35 6.7% Leu (L) 35 6.7% Lys (K) 37 7.1% Met (M) 11 2.1% Phe (F) 19 3.6% Pro (P) 28 5.3% Ser (S) 46 8.8% Thr (T) 20 3.8% Trp (W) 4 0.8% Tyr (Y) 29 5.5% Val (V) 16 3.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 68 Atomic composition: Carbon C 2641 Hydrogen H 4087 Nitrogen N 769 Oxygen O 805 Sulfur S 24 Formula: C2641H4087N769O805S24 Total number of atoms: 8326 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 65960 Abs 0.1% (=1 g/l) 1.095, assuming all pairs of Cys residues form cystines Ext. coefficient 65210 Abs 0.1% (=1 g/l) 1.082, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 51.38 This classifies the protein as unstable. Aliphatic index: 65.53 Grand average of hydropathicity (GRAVY): -0.834