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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQSISLKGS TRTVTEFFEY SINSILYQRG VYPAEDFVTV KKYDLTLLKT HDDELKDYIR

70 80 90 100 110 120
KILLQVHRWL LGGKCNQLVL CIVDKDEGEV VERWSFNVQH ISGNSNGQDD VVDLNTTQSQ

130 140 150 160 170 180
IRALIRQITS SVTFLPELTK EGGYTFTVLA YTDADAKVPL EWADSNSKEI PDGEVVQFKT

190
FSTNDHKVGA QVSYKY


References and documentation are available.

Number of amino acids: 196 Molecular weight: 22284.08 Theoretical pI: 5.24
Amino acid composition: 
Ala (A) 7 3.6% Arg (R) 7 3.6% Asn (N) 8 4.1% Asp (D) 15 7.7% Cys (C) 2 1.0% Gln (Q) 11 5.6% Glu (E) 12 6.1% Gly (G) 11 5.6% His (H) 4 2.0% Ile (I) 11 5.6% Leu (L) 18 9.2% Lys (K) 14 7.1% Met (M) 1 0.5% Phe (F) 8 4.1% Pro (P) 4 2.0% Ser (S) 16 8.2% Thr (T) 16 8.2% Trp (W) 3 1.5% Tyr (Y) 9 4.6% Val (V) 19 9.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 27 Total number of positively charged residues (Arg + Lys): 21 Atomic composition: Carbon C 998 Hydrogen H 1557 Nitrogen N 261 Oxygen O 311 Sulfur S 3 Formula: C998H1557N261O311S3 Total number of atoms: 3130 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 30035 Abs 0.1% (=1 g/l) 1.348, assuming all pairs of Cys residues form cystines Ext. coefficient 29910 Abs 0.1% (=1 g/l) 1.342, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 28.42 This classifies the protein as stable. Aliphatic index: 89.39 Grand average of hydropathicity (GRAVY): -0.355