ProtParam
User-provided sequence:
10 20 30 40 50 60
MSQVYFDVEA DGQPIGRVVF KLYNDIVPKT AENFRALCTG EKGFGYAGSP FHRVIPDFML
70 80 90 100 110 120
QGGDFTAGNG TGGKSIYGGK FPDENFKKHH DRPGLLSMAN AGPNTNGSQF FITTVPCPWL
130 140 150 160
DGKHVVFGEV VDGYDIVKKV ESLGSPSGAT KARIVVAKSG EL
References and
documentation are available.
Number of amino acids: 162
Molecular weight: 17390.69
Theoretical pI: 6.90
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 17
Atomic composition:
Carbon C 784
Hydrogen H 1197
Nitrogen N 209
Oxygen O 230
Sulfur S 5
Formula: C
784H
1197N
209O
230S
5
Total number of atoms: 2425
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 13075
Abs 0.1% (=1 g/l) 0.752, assuming all pairs of Cys residues form cystines
Ext. coefficient 12950
Abs 0.1% (=1 g/l) 0.745, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 19.17
This classifies the protein as stable.
Aliphatic index: 69.14
Grand average of hydropathicity (GRAVY): -0.236