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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSQYIKCYGR VRPSARLGAS SESLVVGGRV VTIDTDNGSK RYELHHIFDS SSSQEDVFGT

70 80 90 100 110 120
VAKKIVEDCV EGYNGTVFAY GQTGSGKTHT MLGPCDSWTD PELMGLIPRS VEHVFQHLDT

130 140 150 160 170 180
KAKKCQKLTF SVSVEFVELY NEVIYDLLNA KNKVQLRDSG KDIQLVGALP KNVDNPLDLM

190 200 210 220 230 240
HLVQKGWQER STGSTAMNAE SHALLIIRIK TQERTGELVK ERSSILNLVD LAGSERQTHT

250 260 270 280 290 300
KSSGDRLKEA TNINSSLTVL GRCIRLLADP SKAKGHVPYR DSHLTHILKN SLGGNSKTAV

310 320 330 340 350 360
IVNMHPDRDF AQESNSTLMF AQSCTMIMNI ATRNEVMTGD QESSYKKAIQ QLRQEKRGKS

370 380 390 400 410 420
TANSSSTFEC IALKNQTLQL EIDASEKRYQ ELQKETSALR NRYQENLDAT ILMQTPSAKE

430 440 450 460 470 480
RRSSSRPKRR ETQYRPSPAR MALFAEVETS EDAVLDLQCQ NEKLCCELSS LKDKHEEATS

490 500 510 520 530 540
KSTETERLLQ GEIVALQKEV SIVSESLRKS EAVAEGYKEK VAANNLTLDK LLLHIDASRK

550 560 570 580 590 600
RIAELELSSK ESENRSSEEL EVDELQLSNA TIKKLNADLS TKAGLIRSLE DSIEKKSQMI

610 620 630 640 650 660
TRLEEQAVLD SSELSSTKRQ LEHSRLEAIQ WRKISDETTS AMQTQLKDHQ TDIDQCRHKK

670 680 690
KSEIQSMQLS LDNANARVKE SEAMMKKTSG


References and documentation are available.

Number of amino acids: 690 Molecular weight: 77322.28 Theoretical pI: 7.00
Amino acid composition: 
Ala (A) 46 6.7% Arg (R) 42 6.1% Asn (N) 29 4.2% Asp (D) 36 5.2% Cys (C) 11 1.6% Gln (Q) 39 5.7% Glu (E) 63 9.1% Gly (G) 30 4.3% His (H) 17 2.5% Ile (I) 33 4.8% Leu (L) 72 10.4% Lys (K) 56 8.1% Met (M) 17 2.5% Phe (F) 10 1.4% Pro (P) 13 1.9% Ser (S) 78 11.3% Thr (T) 45 6.5% Trp (W) 3 0.4% Tyr (Y) 13 1.9% Val (V) 37 5.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 99 Total number of positively charged residues (Arg + Lys): 98 Atomic composition: Carbon C 3310 Hydrogen H 5453 Nitrogen N 977 Oxygen O 1093 Sulfur S 28 Formula: C3310H5453N977O1093S28 Total number of atoms: 10861 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 36495 Abs 0.1% (=1 g/l) 0.472, assuming all pairs of Cys residues form cystines Ext. coefficient 35870 Abs 0.1% (=1 g/l) 0.464, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.94 This classifies the protein as unstable. Aliphatic index: 81.57 Grand average of hydropathicity (GRAVY): -0.644