ProtParam
User-provided sequence:
10 20 30 40 50 60
MSRHQYDLIQ CMKQPGKSIG LLCSNCDGKC PICDSFVKPT EQVRICQDCS QGHLSNKCIL
70 80 90 100 110
CANNLGENNE NGVSAYYCLE CVRLEKHREG CPRIINVGGT KTDMIYMKKK DNKSSLQGF
References and
documentation are available.
Number of amino acids: 119
Molecular weight: 13326.39
Theoretical pI: 8.45
Total number of negatively charged residues (Asp + Glu): 12
Total number of positively charged residues (Arg + Lys): 16
Atomic composition:
Carbon C 561
Hydrogen H 913
Nitrogen N 167
Oxygen O 176
Sulfur S 16
Formula: C
561H
913N
167O
176S
16
Total number of atoms: 1833
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 6710
Abs 0.1% (=1 g/l) 0.504, assuming all pairs of Cys residues form cystines
Ext. coefficient 5960
Abs 0.1% (=1 g/l) 0.447, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 51.11
This classifies the protein as unstable.
Aliphatic index: 69.58
Grand average of hydropathicity (GRAVY): -0.503