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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSRLERLTSL NVVAGSDLRR TSIIGTIGPK TNNPETLVAL RKAGLNIVRM NFSHGSYEYH

70 80 90 100 110 120
KSVIDNARKS EELYPGRPLA IALDTKGPEI RTGTTTNDVD YPIPPNHEMI FTTDDKYAKA

130 140 150 160 170 180
CDDKIMYVDY KNITKVISAG RIIYVDDGVL SFQVLEVVDD KTLKVKALNA GKICSHKGVN

190 200 210 220 230 240
LPGTDVDLPA LSEKDKEDLR FGVKNGVHMV FASFIRTAND VLTIREVLGE QGKDVKIIVK

250 260 270 280 290 300
IENQQGVNNF DEILKVTDGV MVARGDLGIE IPAPEVLAVQ KKLIAKSNLA GKPVICATQM

310 320 330 340 350 360
LESMTYNPRP TRAEVSDVGN AILDGADCVM LSGETAKGNY PINAVTTMAE TAVIAEQAIA

370 380 390 400 410 420
YLPNYDDMRN CTPKPTSTTE TVAASAVAAV FEQKAKAIIV LSTSGTTPRL VSKYRPNCPI

430 440 450 460 470 480
ILVTRCPRAA RFSHLYRGVF PFVFEKEPVS DWTDDVEARI NFGIEKAKEF GILKKGDTYV

490 500
SIQGFKAGAG HSNTLQVSTV


References and documentation are available.

Number of amino acids: 500 Molecular weight: 54544.63 Theoretical pI: 7.56
Amino acid composition: 
Ala (A) 43 8.6% Arg (R) 24 4.8% Asn (N) 26 5.2% Asp (D) 32 6.4% Cys (C) 7 1.4% Gln (Q) 10 2.0% Glu (E) 28 5.6% Gly (G) 34 6.8% His (H) 7 1.4% Ile (I) 37 7.4% Leu (L) 35 7.0% Lys (K) 37 7.4% Met (M) 11 2.2% Phe (F) 15 3.0% Pro (P) 25 5.0% Ser (S) 27 5.4% Thr (T) 38 7.6% Trp (W) 1 0.2% Tyr (Y) 15 3.0% Val (V) 48 9.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 60 Total number of positively charged residues (Arg + Lys): 61 Atomic composition: Carbon C 2414 Hydrogen H 3906 Nitrogen N 660 Oxygen O 737 Sulfur S 18 Formula: C2414H3906N660O737S18 Total number of atoms: 7735 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 28225 Abs 0.1% (=1 g/l) 0.517, assuming all pairs of Cys residues form cystines Ext. coefficient 27850 Abs 0.1% (=1 g/l) 0.511, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 23.23 This classifies the protein as stable. Aliphatic index: 92.60 Grand average of hydropathicity (GRAVY): -0.148