ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSRLLEKPNI AMSIKSTGSQ LSSTMTTASA TLSSDLDDAD TSRTQLSPSE TSGVVLVPAT 

        70         80         90        100        110        120 
TVTPMRQKID QVVISLISGA AAGALAKTVI APLDRTKINF QIRNDVPFSF RASLRYLQNT 

       130        140        150        160        170        180 
YANEGVLALW RGNSATMARI VPYAAIQFTA HEQWRRILHV DKDGTNTKGR RFLAGSLAGI 

       190        200        210        220        230        240 
TSQSLTYPLD LARARMAVTD RYTGYRTLRQ VFTKIWVEEG PRTLFRGYWA TVLGVIPYAG 

       250        260        270        280        290        300 
TSFFTYETLK REYYEVVGNN KPNTLVSLAF GAAAGAAGQT ASYPLDIVRR RMQTMRVNTA 

       310        320        330        340        350        360 
GGDRYPTILE TLVKIYREEG VKNGFYKGLS MNWIKGPIAV GISFSTYDLI KAWLTELANL 


RRVEK 

References and documentation are available.

Number of amino acids: 365

Molecular weight: 40368.33

Theoretical pI: 9.99

Amino acid composition: 
Ala (A)  37	 10.1%
Arg (R)  29	  7.9%
Asn (N)  14	  3.8%
Asp (D)  14	  3.8%
Cys (C)   0	  0.0%
Gln (Q)  12	  3.3%
Glu (E)  14	  3.8%
Gly (G)  26	  7.1%
His (H)   2	  0.5%
Ile (I)  21	  5.8%
Leu (L)  34	  9.3%
Lys (K)  16	  4.4%
Met (M)   9	  2.5%
Phe (F)  12	  3.3%
Pro (P)  14	  3.8%
Ser (S)  27	  7.4%
Thr (T)  37	 10.1%
Trp (W)   6	  1.6%
Tyr (Y)  16	  4.4%
Val (V)  25	  6.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 28
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      1804
Hydrogen    H	      2882
Nitrogen    N	       504
Oxygen      O	       528
Sulfur      S	         9

Formula: C1804H2882N504O528S9
Total number of atoms: 5727

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    56840
Abs 0.1% (=1 g/l)   1.408

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 29.40
This classifies the protein as stable.



Aliphatic index: 88.77

Grand average of hydropathicity (GRAVY): -0.134