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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSRLLQTPFL PSVSLPTKTR SSVTGFRVKP RIIPIQAKIR EIFMPALSST MTEGKIVSWV

70 80 90 100 110 120
KSEGDKLNKG ESVVVVESDK ADMDVETFYD GYLAAIMVEE GGVAPVGSAI ALLAETEDEI

130 140 150 160 170 180
ADAKAKASGG GGGGDSKAPP ASPPTAAVEA PVSVEKKVAA APVSIKAVAA SAVHPASEGG

190 200 210 220 230 240
KRIVASPYAK KLAKELKVEL AGLVGSGPMG RIVAKDVEAV AAGGGVQAAV AVKEVVAAPG

250 260 270 280 290 300
VELGSVVPFT TMQGAVSRNM VESLGVPTFR VGYTISTDAL DALYKKIKSK GVTMTALLAK

310 320 330 340 350 360
ATALALAKHP VVNSSCRDGN SFVYNSSINV AVAVAIDGGL ITPVLQNADK VDIYSLSRKW

370 380 390 400 410 420
KELVDKARAK QLQPQEYNTG TFTLSNLGMF GVDRFDAILP PGTGAIMAVG ASQPSVVATK

430 440 450 460
DGRIGMKNQM QVNVTADHRV IYGADLAQFL QTLASIIEDP KDLTF


References and documentation are available.

Number of amino acids: 465 Molecular weight: 48306.78 Theoretical pI: 8.80
Amino acid composition: 
Ala (A) 63 13.5% Arg (R) 15 3.2% Asn (N) 11 2.4% Asp (D) 23 4.9% Cys (C) 1 0.2% Gln (Q) 13 2.8% Glu (E) 23 4.9% Gly (G) 41 8.8% His (H) 3 0.6% Ile (I) 24 5.2% Leu (L) 33 7.1% Lys (K) 35 7.5% Met (M) 13 2.8% Phe (F) 12 2.6% Pro (P) 26 5.6% Ser (S) 37 8.0% Thr (T) 26 5.6% Trp (W) 2 0.4% Tyr (Y) 9 1.9% Val (V) 55 11.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 2146 Hydrogen H 3509 Nitrogen N 577 Oxygen O 654 Sulfur S 14 Formula: C2146H3509N577O654S14 Total number of atoms: 6900 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 24410 Abs 0.1% (=1 g/l) 0.505, assuming all pairs of Cys residues form cystines Ext. coefficient 24410 Abs 0.1% (=1 g/l) 0.505, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.14 This classifies the protein as stable. Aliphatic index: 95.66 Grand average of hydropathicity (GRAVY): 0.131