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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSRPEHIAPP EIFYNDVEAG KYSTNTRIQS IQTEMSERAL ELLDAEGPSF ILDIGCGSGI

70 80 90 100 110 120
STQIGESQGH VVVGMDISPS MLSVALESQE IEGDLLLCDM GTGVPFRPGT FDGVISISAI

130 140 150 160 170 180
QWLLNADKTC NVPQRRLNRF FQTLYISMKR GGRAVMQYYP ETEKSQQMIM DTARKAGFAG

190 200 210 220 230 240
GIVVDHPESK RQKKYYLVLQ AGGTRTLDIS SMTLDQEGTN AKQRKLKKKQ DMSTREYIIH

250 260
KKELNRKRGR LHVPKDSKYS GRRRKAAF


References and documentation are available.

Number of amino acids: 268 Molecular weight: 30083.44 Theoretical pI: 9.33
Amino acid composition: 
Ala (A) 15 5.6% Arg (R) 20 7.5% Asn (N) 7 2.6% Asp (D) 14 5.2% Cys (C) 3 1.1% Gln (Q) 16 6.0% Glu (E) 17 6.3% Gly (G) 23 8.6% His (H) 5 1.9% Ile (I) 19 7.1% Leu (L) 20 7.5% Lys (K) 19 7.1% Met (M) 11 4.1% Phe (F) 8 3.0% Pro (P) 11 4.1% Ser (S) 22 8.2% Thr (T) 15 5.6% Trp (W) 1 0.4% Tyr (Y) 9 3.4% Val (V) 13 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 31 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 1312 Hydrogen H 2123 Nitrogen N 381 Oxygen O 400 Sulfur S 14 Formula: C1312H2123N381O400S14 Total number of atoms: 4230 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 19035 Abs 0.1% (=1 g/l) 0.633, assuming all pairs of Cys residues form cystines Ext. coefficient 18910 Abs 0.1% (=1 g/l) 0.629, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 57.53 This classifies the protein as unstable. Aliphatic index: 76.42 Grand average of hydropathicity (GRAVY): -0.532