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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSRSLLVENS RTINSNEEKG VNESQYILQK RNVPRTILGN VTNNANILQE ISMNRKIGMK

70 80 90 100 110 120
NFSKLNNFFP LKDDVSRADD FTSSFNDSRQ GVKQEVLNNK ENIPEYGYSE QEKQQCSNDD

130 140 150 160 170 180
SFHTNSTALS CNRLIYSENK SISTQMEWQK KIMREDSKKK RPISTLVEQD DQKKFKLHEL

190 200 210 220 230 240
TTEEEVLEEY EWDDLDEEDC DDPLMVSEEV NDIFDYLHHL EIITLPNKAN LYKHKNIKQN

250 260 270 280 290 300
RDILVNWIIK IHNKFGLLPE TLYLAINIMD RFLCEEVVQL NRLQLVGTSC LFIASKYEEI

310 320 330 340 350 360
YSPSIKHFAY ETDGACSVED IKEGERFILE KLDFQISFAN PMNFLRRISK ADDYDIQSRT

370 380 390 400 410 420
LAKFLMEISI VDFKFIGILP SLCASAAMFL SRKMLGKGTW DGNLIHYSGG YTKAKLYPVC

430 440 450 460 470
QLLMDYLVGS TIHDEFLKKY QSRRFLKASI ISIEWALKVR KNGYDIMTLH E


References and documentation are available.

Number of amino acids: 471 Molecular weight: 54870.51 Theoretical pI: 5.64
Amino acid composition: 
Ala (A) 17 3.6% Arg (R) 21 4.5% Asn (N) 34 7.2% Asp (D) 31 6.6% Cys (C) 8 1.7% Gln (Q) 19 4.0% Glu (E) 40 8.5% Gly (G) 17 3.6% His (H) 10 2.1% Ile (I) 39 8.3% Leu (L) 48 10.2% Lys (K) 40 8.5% Met (M) 13 2.8% Phe (F) 22 4.7% Pro (P) 11 2.3% Ser (S) 39 8.3% Thr (T) 19 4.0% Trp (W) 5 1.1% Tyr (Y) 18 3.8% Val (V) 20 4.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 71 Total number of positively charged residues (Arg + Lys): 61 Atomic composition: Carbon C 2440 Hydrogen H 3840 Nitrogen N 652 Oxygen O 743 Sulfur S 21 Formula: C2440H3840N652O743S21 Total number of atoms: 7696 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 54820 Abs 0.1% (=1 g/l) 0.999, assuming all pairs of Cys residues form cystines Ext. coefficient 54320 Abs 0.1% (=1 g/l) 0.990, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.03 This classifies the protein as unstable. Aliphatic index: 87.96 Grand average of hydropathicity (GRAVY): -0.498