Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSESPQDQP QKEQISNNVG VTTNSTSNEE TSRSQDDNVK EVNGNDDTKE EEQEEDAELD

70 80 90 100 110 120
DLFGDDNDDD DDDDVKKSET EKSDSDSDED DEGENINHRS RHRESLGLDD DEAEEQAMYT

130 140 150 160 170 180
RKFYGEDANN FSDQDETTHT FKEENVELVR HIIPSKANVN ETASHNEIFY ARIPNFLTID

190 200 210 220 230 240
PIPFDPPSFE AKVNERASNS ASREDQLDDR LIDENTVRWR YSRDKDQHVF KESNTQIVQW

250 260 270 280 290 300
SDGTYSLKVG EECTDILVND TSNTFLTVSH DQQELIQCYE GGEIKKTLMF IPTSTNSKIH

310 320 330 340 350 360
QKLSKAVIRR NQRQSKGPGT YIVSMDPEVE KKELERKQSQ ILRDRRRRQL KEKEKQESPD

370 380 390 400 410 420
AAFETGFRKQ NSPTTYGASR RNEYEEDDFL VDDDEEEEAA FDDEEDDNEE EEEEEDADEE

430 440 450 460
NASRLRNLKR EGAAMYREEE EEEKDRSETK RRRVAVIEDD EDED


References and documentation are available.

Number of amino acids: 464 Molecular weight: 53920.11 Theoretical pI: 4.32
Amino acid composition: 
Ala (A) 21 4.5% Arg (R) 33 7.1% Asn (N) 30 6.5% Asp (D) 59 12.7% Cys (C) 2 0.4% Gln (Q) 23 5.0% Glu (E) 74 15.9% Gly (G) 15 3.2% His (H) 8 1.7% Ile (I) 19 4.1% Leu (L) 20 4.3% Lys (K) 29 6.2% Met (M) 5 1.1% Phe (F) 15 3.2% Pro (P) 13 2.8% Ser (S) 38 8.2% Thr (T) 27 5.8% Trp (W) 2 0.4% Tyr (Y) 10 2.2% Val (V) 21 4.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 133 Total number of positively charged residues (Arg + Lys): 62 Atomic composition: Carbon C 2258 Hydrogen H 3517 Nitrogen N 663 Oxygen O 859 Sulfur S 7 Formula: C2258H3517N663O859S7 Total number of atoms: 7304 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 26025 Abs 0.1% (=1 g/l) 0.483, assuming all pairs of Cys residues form cystines Ext. coefficient 25900 Abs 0.1% (=1 g/l) 0.480, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 70.43 This classifies the protein as unstable. Aliphatic index: 50.43 Grand average of hydropathicity (GRAVY): -1.477