ProtParam
User-provided sequence:
10 20 30 40 50 60
MSSFYTVVGV FIVVSAMSVL FWIMAPKNNQ AVWRSTVILT LAMMFLMWAI TFLCQLHPLV
70
APRRSDLRPE FAE
References and
documentation are available.
Number of amino acids: 73
Molecular weight: 8381.10
Theoretical pI: 9.30
Total number of negatively charged residues (Asp + Glu): 3
Total number of positively charged residues (Arg + Lys): 5
Atomic composition:
Carbon C 391
Hydrogen H 605
Nitrogen N 95
Oxygen O 95
Sulfur S 7
Formula: C
391H
605N
95O
95S
7
Total number of atoms: 1193
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 17990
Abs 0.1% (=1 g/l) 2.146, assuming all pairs of Cys residues form cystines
Ext. coefficient 17990
Abs 0.1% (=1 g/l) 2.146, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 58.41
This classifies the protein as unstable.
Aliphatic index: 109.45
Grand average of hydropathicity (GRAVY): 0.842