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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSGSAGAPA LSNNSTNSVA KEKSGNISGD EYLSQEEEVF DGNDIENNET KVYEESLDLD

70 80 90 100 110 120
LERSNRQVWL VRLPMFLAEK WRDRNNLHGQ ELGKIRINKD GSKITLLLNE NDNDSIPHEY

130 140 150 160 170 180
DLELTKKVVE NEYVFTEQNL KKYQQRKKEL EADPEKQRQA YLKKQEREEE LKKKQQQQKR

190 200 210 220 230 240
RNNRKKFNHR VMTDRDGRDR YIPYVKTIPK KTAIVGTVCH ECQVMPSMND PNYHKIVEQR

250 260 270 280 290 300
RNIVKLNNKE RITTLDETVG VTMSHTGMSM RSDNSNFLKV GREKAKSNIK SIRMPKKEIL

310 320 330 340 350 360
DYLFKLFDEY DYWSLKGLKE RTRQPEAHLK ECLDKVATLV KKGPYAFKYT LRPEYKKLKE

370 380 390 400
EERKATLGEL ADEQTGSAGD NAQGDAEADL EDEIEMEDVV


References and documentation are available.

Number of amino acids: 400 Molecular weight: 46605.45 Theoretical pI: 6.72
Amino acid composition: 
Ala (A) 18 4.5% Arg (R) 26 6.5% Asn (N) 28 7.0% Asp (D) 27 6.8% Cys (C) 3 0.8% Gln (Q) 18 4.5% Glu (E) 46 11.5% Gly (G) 19 4.8% His (H) 7 1.8% Ile (I) 16 4.0% Leu (L) 35 8.8% Lys (K) 46 11.5% Met (M) 10 2.5% Phe (F) 8 2.0% Pro (P) 12 3.0% Ser (S) 22 5.5% Thr (T) 19 4.8% Trp (W) 3 0.8% Tyr (Y) 15 3.8% Val (V) 22 5.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 73 Total number of positively charged residues (Arg + Lys): 72 Atomic composition: Carbon C 2023 Hydrogen H 3259 Nitrogen N 587 Oxygen O 649 Sulfur S 13 Formula: C2023H3259N587O649S13 Total number of atoms: 6531 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 38975 Abs 0.1% (=1 g/l) 0.836, assuming all pairs of Cys residues form cystines Ext. coefficient 38850 Abs 0.1% (=1 g/l) 0.834, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.59 This classifies the protein as unstable. Aliphatic index: 70.17 Grand average of hydropathicity (GRAVY): -1.091