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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSKKAKTKN EASSSRGGIG GESIVADCGR NKSTCGYCKS STRFSISHGL WTERLTVNDY

70 80 90 100 110 120
QALLDSGWRR SGCYLYKPEM EKTCCPSYTI RLKASDFVPS KEQQRVRRRI ERFLDGELDA

130 140 150 160 170 180
KPSEQTEDQD VSFSREVSVS VKKSLGAAKR EKNNELEPIM KDLSEQIDNA VQKCIQSGEF

190 200 210 220 230 240
PSNVQIPKAS VKKVFSAKRK KLAEGSEDLL YTSNIAFPIV AAMKHTQTLE KGKNVEENRL

250 260 270 280 290 300
SPEAVSEKLL SAMNKVGEFT GFSVKVSKGH INFLSATQVT SSDRNEGEES LCATTIKSSS

310 320 330 340 350 360
NKLHARKRKL EMHLKRSSFE PEEYELYKRY QMKVHNDKPE SISETSYKRF LVDTPLTEVP

370 380 390 400 410 420
SSGYDDEEKI PLCGFGSFHQ QYRVDDRLIA VGVIDILPKC LSSKYLFWDP DFASLSLGNY

430 440 450 460 470 480
SALQEIDWVK QNQAHCSTLE YYYLGYYIHS CNKMRYKAAY RPSELLCPLR YQWVPFEVAK

490 500 510 520 530 540
PLLDKKPYSV LSNISKVSSS SSSPQASETL LESTSEHEDM EQGDTNDDDD EMYNSDEDSD

550 560 570 580 590 600
SDSSSSRNRS DITNILISLN GPRLRYKDIP RFKNPVVQKQ LESMLVSYRK VVGAELSEIM


VYELR


References and documentation are available.

Number of amino acids: 605 Molecular weight: 68599.23 Theoretical pI: 7.11
Amino acid composition: 
Ala (A) 29 4.8% Arg (R) 34 5.6% Asn (N) 25 4.1% Asp (D) 35 5.8% Cys (C) 13 2.1% Gln (Q) 22 3.6% Glu (E) 52 8.6% Gly (G) 27 4.5% His (H) 10 1.7% Ile (I) 26 4.3% Leu (L) 51 8.4% Lys (K) 53 8.8% Met (M) 12 2.0% Phe (F) 18 3.0% Pro (P) 25 4.1% Ser (S) 81 13.4% Thr (T) 24 4.0% Trp (W) 5 0.8% Tyr (Y) 27 4.5% Val (V) 36 6.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 87 Total number of positively charged residues (Arg + Lys): 87 Atomic composition: Carbon C 2998 Hydrogen H 4754 Nitrogen N 832 Oxygen O 959 Sulfur S 25 Formula: C2998H4754N832O959S25 Total number of atoms: 9568 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 68480 Abs 0.1% (=1 g/l) 0.998, assuming all pairs of Cys residues form cystines Ext. coefficient 67730 Abs 0.1% (=1 g/l) 0.987, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.22 This classifies the protein as unstable. Aliphatic index: 71.69 Grand average of hydropathicity (GRAVY): -0.682