ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSLVTLNNG LKMPLVGLGC WKIDKKVCAN QIYEAIKLGY RLFDGACDYG NEKEVGEGIR 

        70         80         90        100        110        120 
KAISEGLVSR KDIFVVSKLW NNFHHPDHVK LALKKTLSDM GLDYLDLYYI HFPIAFKYVP 

       130        140        150        160        170        180 
FEEKYPPGFY TGADDEKKGH ITEAHVPIID TYRALEECVD EGLIKSIGVS NFQGSLIQDL 

       190        200        210        220        230        240 
LRGCRIKPVA LQIEHHPYLT QEHLVEFCKL HDIQVVAYSS FGPQSFIEMD LQLAKTTPTL 

       250        260        270        280        290        300 
FENDVIKKVS QNHPGSTTSQ VLLRWATQRG IAVIPKSSKK ERLLGNLEIE KKFTLTEQEL 

       310        320 
KDISALNANI RFNDPWTWLD GKFPTFA 

References and documentation are available.

Number of amino acids: 327

Molecular weight: 37118.78

Theoretical pI: 6.60

Amino acid composition: 
Ala (A)  17	  5.2%
Arg (R)  10	  3.1%
Asn (N)  13	  4.0%
Asp (D)  19	  5.8%
Cys (C)   6	  1.8%
Gln (Q)  12	  3.7%
Glu (E)  22	  6.7%
Gly (G)  22	  6.7%
His (H)  11	  3.4%
Ile (I)  24	  7.3%
Leu (L)  36	 11.0%
Lys (K)  29	  8.9%
Met (M)   4	  1.2%
Phe (F)  16	  4.9%
Pro (P)  15	  4.6%
Ser (S)  18	  5.5%
Thr (T)  16	  4.9%
Trp (W)   5	  1.5%
Tyr (Y)  12	  3.7%
Val (V)  20	  6.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1691
Hydrogen    H	      2636
Nitrogen    N	       438
Oxygen      O	       481
Sulfur      S	        10

Formula: C1691H2636N438O481S10
Total number of atoms: 5256

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    45755
Abs 0.1% (=1 g/l)   1.233, assuming all pairs of Cys residues form cystines


Ext. coefficient    45380
Abs 0.1% (=1 g/l)   1.223, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.34
This classifies the protein as stable.



Aliphatic index: 94.50

Grand average of hydropathicity (GRAVY): -0.232