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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSNKGNGRL PSLKDSSSNG GGSAKPSLKF KPKAVARKSK EEREAAASKV KLEEESKRGN

70 80 90 100 110 120
DKKHFNNKNK RVTGAGGQQR RMAKYLNNTH VISSGPLAAG NFVSEKGDLR RGFIKSEGSG

130 140 150 160 170 180
SSLVQKGLET IDNGAESSEN EAEDDDNEGV ASKSKKKFNM GKEFEARNLI EDEDDGESEK

190 200 210 220 230 240
SSDVDMDDEE WRSKRIEQLF PVRPVRVRHE DVETVKREIQ EALSEKPTRE PTPSVKTEPV

250 260 270 280 290 300
GTGLQSYLEE RERQVNEKLA DLGLEKEFQS VDGKEAAAEL ELLNADHQHI LRKLKKMNNK

310 320 330 340 350 360
PERFMVFQLP TRLPAFERPA VKEEKEDMET QASDPSKKKK NIKKKDTKDA LSTRELAGKV

370 380 390 400 410 420
GSIRVHKSGK LSVKIGNVVM DIGKGAETTF LQDVIALSIA DDASSAELLG RVDGKIVVTP


QI


References and documentation are available.

Number of amino acids: 422 Molecular weight: 46667.39 Theoretical pI: 8.59
Amino acid composition: 
Ala (A) 30 7.1% Arg (R) 26 6.2% Asn (N) 21 5.0% Asp (D) 27 6.4% Cys (C) 0 0.0% Gln (Q) 13 3.1% Glu (E) 48 11.4% Gly (G) 32 7.6% His (H) 6 1.4% Ile (I) 15 3.6% Leu (L) 31 7.3% Lys (K) 52 12.3% Met (M) 8 1.9% Phe (F) 12 2.8% Pro (P) 16 3.8% Ser (S) 39 9.2% Thr (T) 15 3.6% Trp (W) 1 0.2% Tyr (Y) 2 0.5% Val (V) 28 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 75 Total number of positively charged residues (Arg + Lys): 78 Atomic composition: Carbon C 2005 Hydrogen H 3305 Nitrogen N 599 Oxygen O 663 Sulfur S 8 Formula: C2005H3305N599O663S8 Total number of atoms: 6580 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 8480 Abs 0.1% (=1 g/l) 0.182 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.86 This classifies the protein as unstable. Aliphatic index: 68.86 Grand average of hydropathicity (GRAVY): -0.944