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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSNSWADVS ESERAPSGGG WGYSRPSRTN YVPPHLRSRT PSSEFVAPSP GNNDRGGYGG

70 80 90 100 110 120
ANSGYGGRGQ GYGGRGSGYG GRGGPVGGWN ARSGGWDRRD TETNPFGNDG NADPAVNEQE

130 140 150 160 170 180
NTVINFEAYE DIPIETSGDN VPPPVNTFAE IDLGEALNLN IQRCKYVKPT PVQRNAIPIL

190 200 210 220 230 240
AAGRDLMACA QTGSGKTAAF CFPIISGIMK DQHIERPRGV RGVYPLAVIL SPTRELACQI

250 260 270 280 290 300
HDEARKFSYQ TGVKVVVAYG GTPVNQQIRE LERGVDILVA TPGRLNDLLE RGRVSLQMVR

310 320 330 340 350 360
FLALDEADRM LDMGFEPQIR KIVQQMDMPP PGVRQTMLFS ATFPREIQRL ASDFLSNYIF

370 380 390 400 410 420
LAVGRVGSST DLIVQRVEFV HDSDKRSHLM DLLHAQRENG NQGKQALTLV FVETKKGADS

430 440 450 460 470 480
LENWLCINGF PATTIHGDRS QQEREVALRS FKTGRTPILV ATDVAARGLD IPHVAHVVNF

490 500 510 520 530 540
DLPNDIDDYV HRIGRTGRAG NSGLATAFFN DNNTTMAKPL AELMQEANQE VPDWLTRYAS

550 560 570 580 590 600
RASFGGGKNR RSGGRFGGRD FRRESFSRGG GGADYYGGGG GYGGVPGGGY GAMPGGYGPV

610 620 630 640
PGGGYGNVPG GGYAPYGRGG GAYYGPGGYG TVPNQGYGPG VASAWD


References and documentation are available.

Number of amino acids: 646 Molecular weight: 69242.07 Theoretical pI: 7.66
Amino acid composition: 
Ala (A) 50 7.7% Arg (R) 53 8.2% Asn (N) 34 5.3% Asp (D) 36 5.6% Cys (C) 5 0.8% Gln (Q) 25 3.9% Glu (E) 30 4.6% Gly (G) 100 15.5% His (H) 10 1.5% Ile (I) 26 4.0% Leu (L) 38 5.9% Lys (K) 14 2.2% Met (M) 13 2.0% Phe (F) 24 3.7% Pro (P) 43 6.7% Ser (S) 38 5.9% Thr (T) 30 4.6% Trp (W) 7 1.1% Tyr (Y) 26 4.0% Val (V) 44 6.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 66 Total number of positively charged residues (Arg + Lys): 67 Atomic composition: Carbon C 3027 Hydrogen H 4683 Nitrogen N 905 Oxygen O 932 Sulfur S 18 Formula: C3027H4683N905O932S18 Total number of atoms: 9565 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 77490 Abs 0.1% (=1 g/l) 1.119, assuming all pairs of Cys residues form cystines Ext. coefficient 77240 Abs 0.1% (=1 g/l) 1.116, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.22 This classifies the protein as unstable. Aliphatic index: 66.13 Grand average of hydropathicity (GRAVY): -0.499