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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSQAFTSVH PNAATSDVNV TIDTFVAKLK RRQVQGSYAI ALETLQLLMR FISAARWNHV

70 80 90 100 110 120
NDLIEQIRDL GNSLEKAHPT AFSCGNVIRR ILAVLRDEVE EDTMSTTVTS TSVAEPLISS

130 140 150 160 170 180
MFNLLQKPEQ PHQNRKNSSG SSSMKTKTDY RQVAIQGIKD LIDEIKNIDE GIQQIAIDLI

190 200 210 220 230 240
HDHEILLTPT PDSKTVLKFL ITARERSNRT FTVLVTEGFP NNTKNAHEFA KKLAQHNIET

250 260 270 280 290 300
LVVPDSAVFA LMSRVGKVII GTKAVFVNGG TISSNSGVSS VCECAREFRT PVFAVAGLYK

310 320 330 340 350 360
LSPLYPFDVE KFVEFGGSQR ILPRMDPRKR LDTVNQITDY VPPENIDIYI TNVGGFNPSF

370 380
IYRIAWDNYK QIDVHLDKNK A


References and documentation are available.

Number of amino acids: 381 Molecular weight: 42569.58 Theoretical pI: 7.74
Amino acid composition: 
Ala (A) 26 6.8% Arg (R) 21 5.5% Asn (N) 23 6.0% Asp (D) 22 5.8% Cys (C) 3 0.8% Gln (Q) 16 4.2% Glu (E) 20 5.2% Gly (G) 17 4.5% His (H) 9 2.4% Ile (I) 31 8.1% Leu (L) 29 7.6% Lys (K) 22 5.8% Met (M) 7 1.8% Phe (F) 18 4.7% Pro (P) 17 4.5% Ser (S) 30 7.9% Thr (T) 28 7.3% Trp (W) 2 0.5% Tyr (Y) 8 2.1% Val (V) 32 8.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 42 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1891 Hydrogen H 3023 Nitrogen N 525 Oxygen O 571 Sulfur S 10 Formula: C1891H3023N525O571S10 Total number of atoms: 6020 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 23045 Abs 0.1% (=1 g/l) 0.541, assuming all pairs of Cys residues form cystines Ext. coefficient 22920 Abs 0.1% (=1 g/l) 0.538, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 46.09 This classifies the protein as unstable. Aliphatic index: 92.60 Grand average of hydropathicity (GRAVY): -0.211