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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSQFPSSPY RTVDPYSPPN YKQQPNCPSS NYEKAGKTAS ESIGNFGKGD YPTPFPSSSI

70 80 90 100 110 120
GRVSSPVRSN KVDAIPSSPA FPGQLAETSP KFSSKLSSPS RHTRVINAEL DPSKISTITV

130 140 150 160 170 180
GRNSSQCDVA LCKNKFISRV HASITYLPQT NEVKIHCFSM NGLIVTYRKQ FDCYQLKDTM

190 200 210 220 230 240
NNNNRAYRLV PRFSNEKCVK EIQDEGGFIN FTLEEGDTVY MTYYKGIMLD FRQVLLRISL

250 260 270 280 290 300
KEKNSSSEPL RFEKKAEFES ESETKHMGSI RKHPLIFTDT SMDRPKKILK DSNKISIGSD

310 320 330 340 350 360
SGVAERMLNH FLNSKSSPLS SVSSVDHEEQ TLRQDSLSSD KNPMTMKKPK LNKRVLPSKP

370 380 390 400 410 420
KKSVKENLDE LSRRNIDVMH LQHILTNHLA FANVQQTPLF QLQQVNSQIS ELSRDELRSI

430 440 450 460 470 480
LSDAKCVGVI YRHGKDAAGK PLDEEYFYDL ENDDDYERRN LVSSLKGGRT GLRSCRRTHK


QYFWKKPAK


References and documentation are available.

Number of amino acids: 489 Molecular weight: 55467.76 Theoretical pI: 9.40
Amino acid composition: 
Ala (A) 17 3.5% Arg (R) 30 6.1% Asn (N) 29 5.9% Asp (D) 27 5.5% Cys (C) 8 1.6% Gln (Q) 20 4.1% Glu (E) 28 5.7% Gly (G) 21 4.3% His (H) 12 2.5% Ile (I) 24 4.9% Leu (L) 38 7.8% Lys (K) 44 9.0% Met (M) 11 2.2% Phe (F) 20 4.1% Pro (P) 30 6.1% Ser (S) 64 13.1% Thr (T) 23 4.7% Trp (W) 1 0.2% Tyr (Y) 17 3.5% Val (V) 25 5.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 55 Total number of positively charged residues (Arg + Lys): 74 Atomic composition: Carbon C 2427 Hydrogen H 3867 Nitrogen N 697 Oxygen O 753 Sulfur S 19 Formula: C2427H3867N697O753S19 Total number of atoms: 7763 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 31330 Abs 0.1% (=1 g/l) 0.565, assuming all pairs of Cys residues form cystines Ext. coefficient 30830 Abs 0.1% (=1 g/l) 0.556, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 56.61 This classifies the protein as unstable. Aliphatic index: 67.75 Grand average of hydropathicity (GRAVY): -0.758