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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSQKVFGIT GPVSTVGATA AENKLNDSLI QELKKEGSFE TEQETANRVQ VLKILQELAQ

70 80 90 100 110 120
RFVYEVSKKK NMSDGMARDA GGKIFTYGSY RLGVHGPGSD IDTLVVVPKH VTREDFFTVF

130 140 150 160 170 180
DSLLRERKEL DEIAPVPDAF VPIIKIKFSG ISIDLICARL DQPQVPLSLT LSDKNLLRNL

190 200 210 220 230 240
DEKDLRALNG TRVTDEILEL VPKPNVFRIA LRAIKLWAQR RAVYANIFGF PGGVAWAMLV

250 260 270 280 290 300
ARICQLYPNA CSAVILNRFF IILSEWNWPQ PVILKPIEDG PLQVRVWNPK IYAQDRSHRM

310 320 330 340 350 360
PVITPAYPSM CATHNITEST KKVILQEFVR GVQITNDIFS NKKSWANLFE KNDFFFRYKF

370 380 390 400 410 420
YLEITAYTRG SDEQHLKWSG LVESKVRLLV MKLEVLAGIK IAHPFTKPFE SSYCCPTEDD

430 440 450 460 470 480
YEMIQDKYGS HKTETALNAL KLVTDENKEE ESIKDAPKAY LSTMYIGLDF NIENKKEKVD

490 500 510 520 530 540
IHIPCTEFVN LCRSFNEDYG DHKVFNLALR FVKGYDLPDE VFDENEKRPS KKSKRKNLDA

550 560
RHETVKRSKS DAASGDNING TTAAVDVN


References and documentation are available.

Number of amino acids: 568 Molecular weight: 64552.06 Theoretical pI: 7.95
Amino acid composition: 
Ala (A) 38 6.7% Arg (R) 30 5.3% Asn (N) 30 5.3% Asp (D) 36 6.3% Cys (C) 8 1.4% Gln (Q) 17 3.0% Glu (E) 40 7.0% Gly (G) 27 4.8% His (H) 10 1.8% Ile (I) 38 6.7% Leu (L) 50 8.8% Lys (K) 48 8.5% Met (M) 9 1.6% Phe (F) 29 5.1% Pro (P) 27 4.8% Ser (S) 35 6.2% Thr (T) 29 5.1% Trp (W) 7 1.2% Tyr (Y) 17 3.0% Val (V) 43 7.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 76 Total number of positively charged residues (Arg + Lys): 78 Atomic composition: Carbon C 2904 Hydrogen H 4582 Nitrogen N 780 Oxygen O 849 Sulfur S 17 Formula: C2904H4582N780O849S17 Total number of atoms: 9132 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 64330 Abs 0.1% (=1 g/l) 0.997, assuming all pairs of Cys residues form cystines Ext. coefficient 63830 Abs 0.1% (=1 g/l) 0.989, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.22 This classifies the protein as unstable. Aliphatic index: 89.07 Grand average of hydropathicity (GRAVY): -0.329