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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSQPFWDER IHRWRCLGSE GNELIYIDEE QTWKDYDPNS LKMNKAGSTG AEVSDVTAEA

70 80 90 100 110 120
TEGKESSNGE DRHTKRLYES TSAEGYPSGS RNKKSKSENS EASPAPVINK AVYIQGLPLD

130 140 150 160 170 180
VTVDEIEEVF KKCGVIAKNI DNGTPRIKIY RTEDGTPKGD ALIVFFRSES VELAEQLFDD

190 200 210 220 230 240
TEFRYGSGQK MRVQKANIDY KKEKTVNKDV GGALKKKALR LRQQQMQQIS SWDDVDEEVD

250 260 270 280 290 300
DKRKKRFNKI VVLKHIFTLE ELDKTPELLI DLKDDITEEA EKCGRVTNVV LYDKEPDGVV

310 320 330 340 350 360
TVRFSNNEEA EACVRLMQGR YFDGRVVEAS IYDGKVRFQK SGKHTLDDEE DEEKRLEKFA


DWLENSN


References and documentation are available.

Number of amino acids: 367 Molecular weight: 41963.76 Theoretical pI: 5.05
Amino acid composition: 
Ala (A) 19 5.2% Arg (R) 22 6.0% Asn (N) 17 4.6% Asp (D) 32 8.7% Cys (C) 4 1.1% Gln (Q) 13 3.5% Glu (E) 42 11.4% Gly (G) 23 6.3% His (H) 4 1.1% Ile (I) 18 4.9% Leu (L) 23 6.3% Lys (K) 37 10.1% Met (M) 5 1.4% Phe (F) 12 3.3% Pro (P) 10 2.7% Ser (S) 25 6.8% Thr (T) 18 4.9% Trp (W) 5 1.4% Tyr (Y) 11 3.0% Val (V) 27 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 74 Total number of positively charged residues (Arg + Lys): 59 Atomic composition: Carbon C 1829 Hydrogen H 2899 Nitrogen N 513 Oxygen O 600 Sulfur S 9 Formula: C1829H2899N513O600S9 Total number of atoms: 5850 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 44140 Abs 0.1% (=1 g/l) 1.052, assuming all pairs of Cys residues form cystines Ext. coefficient 43890 Abs 0.1% (=1 g/l) 1.046, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.28 This classifies the protein as unstable. Aliphatic index: 70.08 Grand average of hydropathicity (GRAVY): -0.893