ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSQQHKFKR PDVSVRDKKL DTLNVQLKKI DTEIGLIRKQ IDQHQVNDTT QQERKKLQDK 

        70         80         90        100        110        120 
NKEIIKIQAD LKTRRSNIHD SIKQLDAQIK RKNNQIEEKL GKKAKFSSTA EAKQRINEIE 

       130        140        150        160        170        180 
ESIASGDLSL VQEKLLVKEM QSLNKLIKDL VNIEPIRKSV DADKAKINQL KEELNGLNPK 

       190        200        210        220        230        240 
DVSNQFEENQ QKLNDIHSKT QGVYDKRQTL FNKRAALYKK RDELYSQIRQ IRADFDNEFK 

       250        260        270        280        290        300 
SFRAKLDKER LKREEEQRLS KLLEQKDVDM GKLQEKLTHA KIPAFTYEIG AIENSLLVLD 

       310        320        330        340        350        360 
PTYVKPKKNI LPDLSSNALE TKPARKVVAD DLVLVTPKKD DFVNVAPSKS KKYKKKNQQK 

       370        380        390        400        410        420 
NTENEQPASI FNKVDGKFTL EPTLIATLAE LDVTVPINSD DVKITVEQLK KKHEELLSKQ 

       430        440        450        460        470 
EEQTKQNIES VEKEIEKLNL DYSNKEQQVK KELEEKRLKE QEESEKDKEN 

References and documentation are available.

Number of amino acids: 470

Molecular weight: 54639.30

Theoretical pI: 9.18

Amino acid composition: 
Ala (A)  22	  4.7%
Arg (R)  20	  4.3%
Asn (N)  30	  6.4%
Asp (D)  35	  7.4%
Cys (C)   0	  0.0%
Gln (Q)  37	  7.9%
Glu (E)  49	 10.4%
Gly (G)   8	  1.7%
His (H)   6	  1.3%
Ile (I)  31	  6.6%
Leu (L)  48	 10.2%
Lys (K)  76	 16.2%
Met (M)   3	  0.6%
Phe (F)  11	  2.3%
Pro (P)  13	  2.8%
Ser (S)  28	  6.0%
Thr (T)  20	  4.3%
Trp (W)   0	  0.0%
Tyr (Y)   7	  1.5%
Val (V)  26	  5.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 84
Total number of positively charged residues (Arg + Lys): 96

Atomic composition:

Carbon      C	      2394
Hydrogen    H	      3987
Nitrogen    N	       685
Oxygen      O	       761
Sulfur      S	         3

Formula: C2394H3987N685O761S3
Total number of atoms: 7830

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10430
Abs 0.1% (=1 g/l)   0.191

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.02
This classifies the protein as unstable.



Aliphatic index: 86.28

Grand average of hydropathicity (GRAVY): -1.056