ProtParam
User-provided sequence:
10 20 30 40 50 60
MSSRIIVGSA ALAAAITASI MVREQKAKGQ RREGNVSAYY NGQEYGSSAP PQLGKLHNIK
70 80 90 100 110 120
QGIKEDALSL KDALLGVSQK AREEAPKVTK RVISPEEDAQ TRKQLGQKAK DSSSQSIFNW
130 140 150 160 170 180
GFSEAERRKA IAIGEFDTAK KRFEEAVDRN EKELLSTVMR EKKAALDRAS IEYERYGRAR
190 200 210 220 230 240
DFNELSDKLD QQERNSNPLK RLLKNNTGDA NTEEAAARSV QGWGDTAQEF GREELEEAKR
250 260 270 280 290 300
NASSEPSEAQ KRLDELKKIK EKGWFGYNKG EQSEQQIAER VARGLEGWGE TAAQLSKDEM
310 320 330 340 350 360
DDLRWNYENS KKQLDKNVSD AMDSLSKAKE DLKQYGSHWW SGWTSKVDND KQALKDEAQK
370 380 390
KYDEALKKYD EAKNKFKEWN DKGDGKFWSS KKD
References and
documentation are available.
Number of amino acids: 393
Molecular weight: 44580.42
Theoretical pI: 8.55
Total number of negatively charged residues (Asp + Glu): 71
Total number of positively charged residues (Arg + Lys): 74
Atomic composition:
Carbon C 1930
Hydrogen H 3077
Nitrogen N 573
Oxygen O 632
Sulfur S 5
Formula: C
1930H
3077N
573O
632S
5
Total number of atoms: 6217
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 69900
Abs 0.1% (=1 g/l) 1.568
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 43.30
This classifies the protein as unstable.
Aliphatic index: 59.24
Grand average of hydropathicity (GRAVY): -1.170