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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSRYRVEYH LKSHRKDEFI DWVKGLLASP FVLHAVSHEG DYNDDLATTQ RVRSQYADIF

70 80 90 100 110 120
KDIEGLIKDK IEFDSRNMSQ DEIEDGASSQ SLNILGQSRL NLLVPSIGTF FTELPLEQAF

130 140 150 160 170 180
LWEDSQRAIS ARRMVAPSFN DIRHILNTAQ IFHFKKQENL HNGKVLRLVT FDGDVTLYED

190 200 210 220 230 240
GGSLVYTNPV IPYILKLLRC GINVGIVTAA GYDEAGTYEN RLKGLIVALH DSTDIPVSQK

250 260 270 280 290 300
QNLTIMGGES SYLFRYYEDP EEDNFGFRQI DKEEWLLPRM KAWSLEDVEK TLDFAERTLN

310 320 330 340 350 360
RLRKRLNLPS EISIIRKVRA VGIVPGERYD EASKRQVPVK LDREQLEEIV LTLQNTLESF

370 380 390 400 410 420
APSRRIQFSC FDGGSDVWCD IGGKDLGVRS LQQFYNPESP IQPSETLHVG DQFAPVGSAN

430 440 450
DFKARLAGCT LWIASPQETV NYLHRLLETD


References and documentation are available.

Number of amino acids: 450 Molecular weight: 51329.96 Theoretical pI: 5.25
Amino acid composition: 
Ala (A) 24 5.3% Arg (R) 31 6.9% Asn (N) 19 4.2% Asp (D) 33 7.3% Cys (C) 4 0.9% Gln (Q) 21 4.7% Glu (E) 34 7.6% Gly (G) 28 6.2% His (H) 10 2.2% Ile (I) 29 6.4% Leu (L) 49 10.9% Lys (K) 21 4.7% Met (M) 5 1.1% Phe (F) 21 4.7% Pro (P) 18 4.0% Ser (S) 34 7.6% Thr (T) 20 4.4% Trp (W) 6 1.3% Tyr (Y) 15 3.3% Val (V) 28 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 67 Total number of positively charged residues (Arg + Lys): 52 Atomic composition: Carbon C 2290 Hydrogen H 3580 Nitrogen N 630 Oxygen O 694 Sulfur S 9 Formula: C2290H3580N630O694S9 Total number of atoms: 7203 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 55600 Abs 0.1% (=1 g/l) 1.083, assuming all pairs of Cys residues form cystines Ext. coefficient 55350 Abs 0.1% (=1 g/l) 1.078, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 56.98 This classifies the protein as unstable. Aliphatic index: 90.98 Grand average of hydropathicity (GRAVY): -0.396