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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSSDIFDVL NIKQKSRSPT NGQVSVPSSS AANRPKPQVT GMQRELFNLL GENQPPVVIK

70 80 90 100 110 120
SGNNFKEKML STSKPSPWSF VEFKANNSVT LRHWVKGSKE LIGDTPKESP YSKFNQHLSI

130 140 150 160 170 180
PSFTKEEYEA FMNENEGTQK SVESEKNHNE NFTNEKKDES KNSWSFEEIE YLFNLCKKYD

190 200 210 220 230 240
LRWFLIFDRY SYNNSRTLED LKEKFYYTCR NYFKASDPSN PLLSSLNFSA EKEIERKKYL

250 260 270 280 290 300
QRLLSRSAAE IAEEEALVVE SKKFEMAAKR TLAERESLLR LLDSPHSDQT ITQYLTSQGM

310 320 330 340 350 360
SQLYNALLAD KTRKRKHDLN IPENPWMKQQ QQFAQHRQLQ QLNVKKSEVK ENLSPKKTKR

370 380 390 400 410 420
QRQEMQTALK RKSESAYAEQ LLKDFNSDER KALGVITHGE KLSPGVYLRS TKLSTFKPAL

430 440 450 460 470
QNKILAILQE LSLPSRPVMP SFDVMERQEE LLKKINTLID LKKHVDKYEA GMSITK


References and documentation are available.

Number of amino acids: 476 Molecular weight: 55212.71 Theoretical pI: 9.36
Amino acid composition: 
Ala (A) 23 4.8% Arg (R) 24 5.0% Asn (N) 31 6.5% Asp (D) 17 3.6% Cys (C) 2 0.4% Gln (Q) 27 5.7% Glu (E) 45 9.5% Gly (G) 12 2.5% His (H) 8 1.7% Ile (I) 17 3.6% Leu (L) 50 10.5% Lys (K) 53 11.1% Met (M) 11 2.3% Phe (F) 21 4.4% Pro (P) 22 4.6% Ser (S) 52 10.9% Thr (T) 22 4.6% Trp (W) 5 1.1% Tyr (Y) 15 3.2% Val (V) 19 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 62 Total number of positively charged residues (Arg + Lys): 77 Atomic composition: Carbon C 2446 Hydrogen H 3894 Nitrogen N 680 Oxygen O 748 Sulfur S 13 Formula: C2446H3894N680O748S13 Total number of atoms: 7781 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 49975 Abs 0.1% (=1 g/l) 0.905, assuming all pairs of Cys residues form cystines Ext. coefficient 49850 Abs 0.1% (=1 g/l) 0.903, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 55.05 This classifies the protein as unstable. Aliphatic index: 71.30 Grand average of hydropathicity (GRAVY): -0.859