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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSSGVYTCN SCVLTFDSSD EQRAHMKSDW HRYNLKRRVA QLPPISFETF DSKVSAAAAS

70 80 90 100 110 120
TSKSAEKEKP VTKKELKRRE KQALLEKKKK LLEIARANML ENMQKSQEGN TPDLSKLSLQ

130 140 150 160 170 180
ENEENKEKEE PKKEEPEQLT EEEMAERVMQ ENVRNRVDIP LEQCLFCEHN KHFKDVEENL

190 200 210 220 230 240
EHMFRTHGFY IPEQKYLVDK IGLVKYMSEK IGLGNICIVC NYQGRTLTAV RQHMLAKRHC

250 260 270 280 290 300
KIPYESEDER LEISEFYDFT SSYANFNSNT TPDNEDDWED VGSDEAGSDD EDLPQEYLYN

310 320 330 340 350 360
DGIELHLPTG IKVGHRSLQR YYKQDLKPEV ILTEGQGTLV AAETRSFLPA FDKKGVQTQQ

370 380 390
RVWQTERFDK KRLDKRSAKF VNNQPHYRDQ LLQ


References and documentation are available.

Number of amino acids: 393 Molecular weight: 45834.40 Theoretical pI: 5.71
Amino acid composition: 
Ala (A) 19 4.8% Arg (R) 23 5.9% Asn (N) 20 5.1% Asp (D) 24 6.1% Cys (C) 7 1.8% Gln (Q) 23 5.9% Glu (E) 46 11.7% Gly (G) 15 3.8% His (H) 11 2.8% Ile (I) 13 3.3% Leu (L) 34 8.7% Lys (K) 37 9.4% Met (M) 9 2.3% Phe (F) 14 3.6% Pro (P) 15 3.8% Ser (S) 27 6.9% Thr (T) 19 4.8% Trp (W) 3 0.8% Tyr (Y) 14 3.6% Val (V) 20 5.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 70 Total number of positively charged residues (Arg + Lys): 60 Atomic composition: Carbon C 1999 Hydrogen H 3153 Nitrogen N 567 Oxygen O 637 Sulfur S 16 Formula: C1999H3153N567O637S16 Total number of atoms: 6372 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 37735 Abs 0.1% (=1 g/l) 0.823, assuming all pairs of Cys residues form cystines Ext. coefficient 37360 Abs 0.1% (=1 g/l) 0.815, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 55.56 This classifies the protein as unstable. Aliphatic index: 66.23 Grand average of hydropathicity (GRAVY): -0.979