ProtParam
User-provided sequence:
10 20 30 40 50 60
MSSSLPRSLL RLGHRKPLFP RYNTFVNSSV ITHTSLLRTR LYSNGTGATS GKKDDKTRNK
70 80 90 100 110 120
PKPLWPQVKS ASTFTFSGIL VIGAVGISAI VIYLILSELF SPSGDTQLFN RAVSMVEKNK
130 140 150 160 170 180
DIRSLLQCDD GITGKERLKA YGELITNDKW TRNRPIVSTK KLDKEGRTHH YMRFHVESKK
190 200 210 220 230
KIALVHLEAK ESKQNYQPDF INMYVDVPGE KRYYLIKPKL HPVSNSKGFL GIRWGPRKD
References and
documentation are available.
Number of amino acids: 239
Molecular weight: 27205.50
Theoretical pI: 10.15
Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 42
Atomic composition:
Carbon C 1224
Hydrogen H 1966
Nitrogen N 348
Oxygen O 343
Sulfur S 5
Formula: C
1224H
1966N
348O
343S
5
Total number of atoms: 3886
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 29910
Abs 0.1% (=1 g/l) 1.099, assuming all pairs of Cys residues form cystines
Ext. coefficient 29910
Abs 0.1% (=1 g/l) 1.099, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 31.10
This classifies the protein as stable.
Aliphatic index: 83.97
Grand average of hydropathicity (GRAVY): -0.526