ProtParam
User-provided sequence:
10 20 30 40 50 60
MSSSLQSNRQ SLNRKVAVMG YPHVGKSALV LRFTQNIFPE RYESTIEDQH SKHIAAFHRD
70 80 90 100 110 120
YHLRVTDTAG QQEYTVFPRS CSLDINGFIL VYAIDDRKSF EMCSNIYEKI VRTYGDTSIP
130 140 150 160 170 180
IVIVGNKTDL STQRVVRAEE GEELARQWDA KFVEITARES NRVHEVFELL LREIEISRGN
190 200
LSPTERPNGN SPKRNPFKDD GKPCSIS
References and
documentation are available.
Number of amino acids: 207
Molecular weight: 23695.66
Theoretical pI: 7.02
Total number of negatively charged residues (Asp + Glu): 28
Total number of positively charged residues (Arg + Lys): 28
Atomic composition:
Carbon C 1038
Hydrogen H 1643
Nitrogen N 303
Oxygen O 321
Sulfur S 6
Formula: C
1038H
1643N
303O
321S
6
Total number of atoms: 3311
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 16055
Abs 0.1% (=1 g/l) 0.678, assuming all pairs of Cys residues form cystines
Ext. coefficient 15930
Abs 0.1% (=1 g/l) 0.672, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 51.67
This classifies the protein as unstable.
Aliphatic index: 78.60
Grand average of hydropathicity (GRAVY): -0.577