ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSSVNANGGY TKPQKYVPGP GDPELPPQLS EFKDKTSDEI LKEMNRMPFF MTKLDETDGA 

        70         80         90        100        110        120 
GGENVELEAL KALAYEGEPH EIAENFKKQG NELYKAKRFK DARELYSKGL AVECEDKSIN 

       130        140        150        160        170        180 
ESLYANRAAC ELELKNYRRC IEDCSKALTI NPKNVKCYYR TSKAFFQLNK LEEAKSAATF 

       190        200        210        220        230        240 
ANQRIDPENK SILNMLSVID RKEQELKAKE EKQQREAQER ENKKIMLESA MTLRNITNIK 

       250        260        270        280        290        300 
THSPVELLNE GKIRLEDPMD FESQLIYPAL IMYPTQDEFD FVGEVSELTT VQELVDLVLE 

       310        320        330        340        350        360 
GPQERFKKEG KENFTPKKVL VFMETKAGGL IKAGKKLTFH DILKKESPDV PLFDNALKIY 

       370        380 
IVPKVESEGW ISKWDKQKAL ERRSV 

References and documentation are available.

Number of amino acids: 385

Molecular weight: 44112.43

Theoretical pI: 5.69

Amino acid composition: 
Ala (A)  26	  6.8%
Arg (R)  16	  4.2%
Asn (N)  21	  5.5%
Asp (D)  19	  4.9%
Cys (C)   5	  1.3%
Gln (Q)  14	  3.6%
Glu (E)  48	 12.5%
Gly (G)  18	  4.7%
His (H)   3	  0.8%
Ile (I)  19	  4.9%
Leu (L)  37	  9.6%
Lys (K)  46	 11.9%
Met (M)  10	  2.6%
Phe (F)  16	  4.2%
Pro (P)  19	  4.9%
Ser (S)  20	  5.2%
Thr (T)  16	  4.2%
Trp (W)   2	  0.5%
Tyr (Y)  12	  3.1%
Val (V)  18	  4.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 67
Total number of positively charged residues (Arg + Lys): 62

Atomic composition:

Carbon      C	      1958
Hydrogen    H	      3130
Nitrogen    N	       522
Oxygen      O	       603
Sulfur      S	        15

Formula: C1958H3130N522O603S15
Total number of atoms: 6228

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29130
Abs 0.1% (=1 g/l)   0.660, assuming all pairs of Cys residues form cystines


Ext. coefficient    28880
Abs 0.1% (=1 g/l)   0.655, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.15
This classifies the protein as unstable.



Aliphatic index: 77.04

Grand average of hydropathicity (GRAVY): -0.715