ProtParam
User-provided sequence:
10 20 30 40 50 60
MSSVNKDTIH VAERSLHKEH LTEGGNMAFH NHLNDFAHIE DPLERRRLAL ESIDDEGFGW
70 80 90 100 110 120
QQVKTISIAG VGFLTDSYDI FAINLGITMM SYVYWHGSMP GPSQTLLKVS TSVGTVIGQF
130 140 150 160 170 180
GFGTLADIVG RKRIYGMELI IMIVCTILQT TVAHSPAINF VAVLTFYRIV MGIGIGGDYP
190 200 210 220 230 240
LSSIITSEFA TTKWRGAIMG AVFANQAWGQ ISGGIIALIL VAAYKGELEY ANSGAECDAR
250 260 270 280 290 300
CQKACDQMWR ILIGLGTVLG LACLYFRLTI PESPRYQLDV NAKLELAAAA QEQDGEKKIH
310 320 330 340 350 360
DTSDEDMAIN GLERASTAVE SLDNHPPKAS FKDFCRHFGQ WKYGKILLGT AGSWFTLDVA
370 380 390 400 410 420
FYGLSLNSAV ILQTIGYAGS KNVYKKLYDT AVGNLILICA GSLPGYWVSV FTVDIIGRKP
430 440 450 460 470 480
IQLAGFIILT ALFCVIGFAY HKLGDHGLLA LYVICQFFQN FGPNTTTFIV PGECFPTRYR
490 500 510 520 530 540
STAHGISAAS GKVGAIIAQT ALGTLIDHNC ARDGKPTNCW LPHVMEIFAL FMLLGIFTTL
550 560 570 580
LIPETKRKTL EEINELYHDE IDPATLNFRN KNNDIESSSP SQLQHEA
References and
documentation are available.
Number of amino acids: 587
Molecular weight: 64382.11
Theoretical pI: 5.98
Total number of negatively charged residues (Asp + Glu): 55
Total number of positively charged residues (Arg + Lys): 45
Atomic composition:
Carbon C 2915
Hydrogen H 4528
Nitrogen N 760
Oxygen O 835
Sulfur S 25
Formula: C
2915H
4528N
760O
835S
25
Total number of atoms: 9063
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 80050
Abs 0.1% (=1 g/l) 1.243, assuming all pairs of Cys residues form cystines
Ext. coefficient 79300
Abs 0.1% (=1 g/l) 1.232, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 36.01
This classifies the protein as stable.
Aliphatic index: 98.59
Grand average of hydropathicity (GRAVY): 0.164