ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTADQEQPK VVEATPEDGT ASSQKSTINA ENENTKQNQS MEPQETSKGT SNDTKDPDNG 

        70         80         90        100        110        120 
EKNEEAAIDE NSNVEAAERK RKHISTDFSD DDLEKEEHND QSLQPTVENR ASKDRDSSAT 

       130        140        150        160        170        180 
PSSRQELEEK LDRILKKPKV RRTRRDEDDL EQYLDEKILR LKDEMNIAAQ LDIDTLNKRI 

       190        200        210        220        230        240 
ETGDTSLIAM QKVKLLPKVV SVLSKANLAD TILDNNLLQS VRIWLEPLPD GSLPSFEIQK 

       250        260        270        280        290        300 
SLFAALNDLP VKTEHLKESG LGRVVIFYTK SKRVEAQLAR LAEKLIAEWT RPIIGASDNY 

       310        320        330        340        350        360 
RDKRIMQLEF DSEKLRKKSV MDSAKNRKKK SKSGEDPTSR GSSVQTLYEQ AAARRNRAAA 

       370        380        390        400        410 
PAQTTTDYKY APVSNLSAVP TNARAVGVGS TLNNSEMYKR LTSRLNKKHK 

References and documentation are available.

Number of amino acids: 410

Molecular weight: 46082.48

Theoretical pI: 6.97

Amino acid composition: 
Ala (A)  34	  8.3%
Arg (R)  28	  6.8%
Asn (N)  25	  6.1%
Asp (D)  32	  7.8%
Cys (C)   0	  0.0%
Gln (Q)  19	  4.6%
Glu (E)  37	  9.0%
Gly (G)  12	  2.9%
His (H)   4	  1.0%
Ile (I)  17	  4.1%
Leu (L)  37	  9.0%
Lys (K)  41	 10.0%
Met (M)   7	  1.7%
Phe (F)   5	  1.2%
Pro (P)  17	  4.1%
Ser (S)  39	  9.5%
Thr (T)  27	  6.6%
Trp (W)   2	  0.5%
Tyr (Y)   7	  1.7%
Val (V)  20	  4.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 69
Total number of positively charged residues (Arg + Lys): 69

Atomic composition:

Carbon      C	      1971
Hydrogen    H	      3253
Nitrogen    N	       589
Oxygen      O	       666
Sulfur      S	         7

Formula: C1971H3253N589O666S7
Total number of atoms: 6486

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    21430
Abs 0.1% (=1 g/l)   0.465

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.38
This classifies the protein as unstable.



Aliphatic index: 73.80

Grand average of hydropathicity (GRAVY): -0.970