ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTAEFAQLL ENSILSPDQN IRLTSETQLK KLSNDNFLQF AGLSSQVLID ENTKLEGRIL 

        70         80         90        100        110        120 
AALTLKNELV SKDSVKTQQF AQRWITQVSP EAKNQIKTNA LTALVSIEPR IANAAAQLIA 

       130        140        150        160        170        180 
AIADIELPHG AWPELMKIMV DNTGAEQPEN VKRASLLALG YMCESADPQS QALVSSSNNI 

       190        200        210        220        230        240 
LIAIVQGAQS TETSKAVRLA ALNALADSLI FIKNNMEREG ERNYLMQVVC EATQAEDIEV 

       250        260        270        280        290        300 
QAAAFGCLCK IMSLYYTFMK PYMEQALYAL TIATMKSPND KVASMTVEFW STICEEEIDI 

       310        320        330        340        350        360 
AYELAQFPQS PLQSYNFALS SIKDVVPNLL NLLTRQNEDP EDDDWNVSMS AGACLQLFAQ 

       370        380        390        400        410        420 
NCGNHILEPV LEFVEQNITA DNWRNREAAV MAFGSIMDGP DKVQRTYYVH QALPSILNLM 

       430        440        450        460        470        480 
NDQSLQVKET TAWCIGRIAD SVAESIDPQQ HLPGVVQACL IGLQDHPKVA TNCSWTIINL 

       490        500        510        520        530        540 
VEQLAEATPS PIYNFYPALV DGLIGAANRI DNEFNARASA FSALTTMVEY ATDTVAETSA 

       550        560        570        580        590        600 
SISTFVMDKL GQTMSVDENQ LTLEDAQSLQ ELQSNILTVL AAVIRKSPSS VEPVADMLMG 

       610        620        630        640        650        660 
LFFRLLEKKD SAFIEDDVFY AISALAASLG KGFEKYLETF SPYLLKALNQ VDSPVSITAV 

       670        680        690        700        710        720 
GFIADISNSL EEDFRRYSDA MMNVLAQMIS NPNARRELKP AVLSVFGDIA SNIGADFIPY 

       730        740        750        760        770        780 
LNDIMALCVA AQNTKPENGT LEALDYQIKV LEAVLDAYVG IVAGLHDKPE ALFPYVGTIF 

       790        800        810        820        830        840 
QFIAQVAEDP QLYSEDATSR AAVGLIGDIA AMFPDGSIKQ FYGQDWVIDY IKRTRSGQLF 

       850        860 
SQATKDTARW AREQQKRQLS L 

References and documentation are available.

Number of amino acids: 861

Molecular weight: 94775.83

Theoretical pI: 4.52

Amino acid composition: 
Ala (A) 102	 11.8%
Arg (R)  27	  3.1%
Asn (N)  47	  5.5%
Asp (D)  50	  5.8%
Cys (C)  11	  1.3%
Gln (Q)  55	  6.4%
Glu (E)  57	  6.6%
Gly (G)  33	  3.8%
His (H)   6	  0.7%
Ile (I)  59	  6.9%
Leu (L)  90	 10.5%
Lys (K)  35	  4.1%
Met (M)  25	  2.9%
Phe (F)  33	  3.8%
Pro (P)  34	  3.9%
Ser (S)  66	  7.7%
Thr (T)  44	  5.1%
Trp (W)   9	  1.0%
Tyr (Y)  24	  2.8%
Val (V)  54	  6.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 107
Total number of positively charged residues (Arg + Lys): 62

Atomic composition:

Carbon      C	      4206
Hydrogen    H	      6652
Nitrogen    N	      1100
Oxygen      O	      1312
Sulfur      S	        36

Formula: C4206H6652N1100O1312S36
Total number of atoms: 13306

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    85885
Abs 0.1% (=1 g/l)   0.906, assuming all pairs of Cys residues form cystines


Ext. coefficient    85260
Abs 0.1% (=1 g/l)   0.900, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 44.75
This classifies the protein as unstable.



Aliphatic index: 97.53

Grand average of hydropathicity (GRAVY): -0.016