ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTAVTFFGQ HVLNRVSFLR CSKEFIKKSL NHDSTVFIPF IEGEALISPE NGDLVQLSNS 

        70         80         90        100        110        120 
VKSYKNILSA IVPLYTTLLN TTRSRSDESG INVTFLGLLE GTDSAFNFEW SNISYKGTPY 

       130        140        150        160        170        180 
FGLDIRVTES TLFKKVDFEP IFSYPKVTRD HIFKQTNEDA SLYSQGKMYL DWLAKYKFCP 

       190        200        210        220        230        240 
GCGSPLFPVE AGTKLQCSNE NRNVYCNVRD ARINNVCFPR TDPTVIIALT NSDYSKCCLA 

       250        260        270        280        290        300 
RSKKRYGDFV LYSTIAGFME PSETIEEACI REIWEETGIS CKNIDIVRSQ PWPYPCSLMI 

       310        320        330        340        350        360 
GCLGIVQFNS KNEVINLNHD DELLDAQWFD TTEIIQALDK YAGGYRVPFK NDINLPGSTT 

       370        380 
IAFQLINHVC ENYKNLRKTS SSHL 

References and documentation are available.

Number of amino acids: 384

Molecular weight: 43516.48

Theoretical pI: 5.94

Amino acid composition: 
Ala (A)  16	  4.2%
Arg (R)  16	  4.2%
Asn (N)  27	  7.0%
Asp (D)  20	  5.2%
Cys (C)  13	  3.4%
Gln (Q)  10	  2.6%
Glu (E)  23	  6.0%
Gly (G)  20	  5.2%
His (H)   6	  1.6%
Ile (I)  29	  7.6%
Leu (L)  33	  8.6%
Lys (K)  23	  6.0%
Met (M)   4	  1.0%
Phe (F)  23	  6.0%
Pro (P)  17	  4.4%
Ser (S)  35	  9.1%
Thr (T)  26	  6.8%
Trp (W)   5	  1.3%
Tyr (Y)  16	  4.2%
Val (V)  22	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 43
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1952
Hydrogen    H	      3013
Nitrogen    N	       509
Oxygen      O	       585
Sulfur      S	        17

Formula: C1952H3013N509O585S17
Total number of atoms: 6076

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    52090
Abs 0.1% (=1 g/l)   1.197, assuming all pairs of Cys residues form cystines


Ext. coefficient    51340
Abs 0.1% (=1 g/l)   1.180, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.64
This classifies the protein as unstable.



Aliphatic index: 83.75

Grand average of hydropathicity (GRAVY): -0.224