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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTGDFLTKG IELVQKAIDL DTATQYEEAY TAYYNGLDYL MLALKYEKNP KSKDLIRAKF

70 80 90 100 110 120
TEYLNRAEQL KKHLESEEAN AAKKSPSAGS GSNGGNKKIS QEEGEDNGGE DNKKLRGALS

130 140 150 160 170 180
SAILSEKPNV KWEDVAGLEG AKEALKEAVI LPVKFPHLFK GNRKPTSGIL LYGPPGTGKS

190 200 210 220 230 240
YLAKAVATEA NSTFFSVSSS DLVSKWMGES EKLVKQLFAM ARENKPSIIF IDEVDALTGT

250 260 270 280 290 300
RGEGESEASR RIKTELLVQM NGVGNDSQGV LVLGATNIPW QLDSAIRRRF ERRIYIPLPD

310 320 330 340 350 360
LAARTTMFEI NVGDTPCVLT KEDYRTLGAM TEGYSGSDIA VVVKDALMQP IRKIQSATHF

370 380 390 400 410 420
KDVSTEDDET RKLTPCSPGD DGAIEMSWTD IEADELKEPD LTIKDFLKAI KSTRPTVNED

430
DLLKQEQFTR DFGQEGN


References and documentation are available.

Number of amino acids: 437 Molecular weight: 48172.32 Theoretical pI: 5.12
Amino acid composition: 
Ala (A) 36 8.2% Arg (R) 19 4.3% Asn (N) 18 4.1% Asp (D) 30 6.9% Cys (C) 2 0.5% Gln (Q) 13 3.0% Glu (E) 40 9.2% Gly (G) 34 7.8% His (H) 3 0.7% Ile (I) 23 5.3% Leu (L) 41 9.4% Lys (K) 39 8.9% Met (M) 9 2.1% Phe (F) 14 3.2% Pro (P) 18 4.1% Ser (S) 32 7.3% Thr (T) 29 6.6% Trp (W) 4 0.9% Tyr (Y) 12 2.7% Val (V) 21 4.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 70 Total number of positively charged residues (Arg + Lys): 58 Atomic composition: Carbon C 2119 Hydrogen H 3390 Nitrogen N 574 Oxygen O 682 Sulfur S 11 Formula: C2119H3390N574O682S11 Total number of atoms: 6776 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 40005 Abs 0.1% (=1 g/l) 0.830, assuming all pairs of Cys residues form cystines Ext. coefficient 39880 Abs 0.1% (=1 g/l) 0.828, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.68 This classifies the protein as stable. Aliphatic index: 79.29 Grand average of hydropathicity (GRAVY): -0.537