ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTLSDSDTE TEVVSRNLCG IVDIGSNGIR FSISSKAAHH ARIMPCVFKD RVGLSLYEVQ 

        70         80         90        100        110        120 
YNTHTNAKCP IPRDIIKEVC SAMKRFKLIC DDFGVPETSV RVIATEATRD AINADEFVNA 

       130        140        150        160        170        180 
VYGSTGWKVE ILGQEDETRV GIYGVVSSFN TVRGLYLDVA GGSTQLSWVI SSHGEVKQSS 

       190        200        210        220        230        240 
KPVSLPYGAG TLLRRMRTDD NRALFYEIKE AYKDAIEKIG IPQEMIDDAK KEGGFDLWTR 

       250        260        270        280        290        300 
GGGLRGMGHL LLYQSEGYPI QTIINGYACT YEEFSSMSDY LFLKQKIPGS SKEHKIFKVS 

       310        320        330        340        350        360 
DRRALQLPAV GLFMSAVFEA IPQIKAVHFS EGGVREGSLY SLLPKEIRAQ DPLLIASRPY 

       370        380        390        400        410        420 
APLLTEKYLY LLRTSIPQED IPEIVNERIA PALCNLAFVH ASYPKELQPT AALHVATRGI 

       430        440        450        460        470        480 
IAGCHGLSHR ARALIGIALC SRWGGNIPES EEKYSQELEQ VVLREGDKAE ALRIVWWTKY 

       490        500        510        520        530        540 
IGTIMYVICG VHPGGNIRDN VFDFHVSKRS EVETSLKELI IDDANTTKVK EESTRKNRGY 

       550        560        570        580 
EVVVRISKDD LKTSASVRSR IITLQKKVRK LSRGSVERVK IGVQFYEE 

References and documentation are available.

Number of amino acids: 588

Molecular weight: 65572.13

Theoretical pI: 8.17

Amino acid composition: 
Ala (A)  40	  6.8%
Arg (R)  39	  6.6%
Asn (N)  16	  2.7%
Asp (D)  28	  4.8%
Cys (C)  10	  1.7%
Gln (Q)  17	  2.9%
Glu (E)  45	  7.7%
Gly (G)  45	  7.7%
His (H)  13	  2.2%
Ile (I)  48	  8.2%
Leu (L)  48	  8.2%
Lys (K)  37	  6.3%
Met (M)   9	  1.5%
Phe (F)  18	  3.1%
Pro (P)  22	  3.7%
Ser (S)  49	  8.3%
Thr (T)  29	  4.9%
Trp (W)   6	  1.0%
Tyr (Y)  23	  3.9%
Val (V)  46	  7.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 73
Total number of positively charged residues (Arg + Lys): 76

Atomic composition:

Carbon      C	      2919
Hydrogen    H	      4659
Nitrogen    N	       807
Oxygen      O	       869
Sulfur      S	        19

Formula: C2919H4659N807O869S19
Total number of atoms: 9273

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    67895
Abs 0.1% (=1 g/l)   1.035, assuming all pairs of Cys residues form cystines


Ext. coefficient    67270
Abs 0.1% (=1 g/l)   1.026, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.91
This classifies the protein as stable.



Aliphatic index: 93.16

Grand average of hydropathicity (GRAVY): -0.211