ProtParam
User-provided sequence:
10 20 30 40 50 60
MSTLSYVSPD ALKGWLMESP NEISIIDVRD YDYEGERIPG SVRIPSDTFL ASVDQHVDDL
70 80 90 100 110 120
MKKRSLIVHC TYSQVRGPKA ARVLSEILRN RITESKEKLS LSQKEKLFQN LPTVYILHGG
130
FSAWKRRYGG QQGLIEYD
References and
documentation are available.
Number of amino acids: 138
Molecular weight: 15778.00
Theoretical pI: 7.84
Total number of negatively charged residues (Asp + Glu): 18
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 702
Hydrogen H 1116
Nitrogen N 194
Oxygen O 211
Sulfur S 4
Formula: C
702H
1116N
194O
211S
4
Total number of atoms: 2227
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 21430
Abs 0.1% (=1 g/l) 1.358, assuming all pairs of Cys residues form cystines
Ext. coefficient 21430
Abs 0.1% (=1 g/l) 1.358, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 53.40
This classifies the protein as unstable.
Aliphatic index: 90.36
Grand average of hydropathicity (GRAVY): -0.451