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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTMSTPAAE QRKLVEQLMG RDFSFRHNRY SHQKRDLGLH DPKICKSYLV GECPYDLFQG

70 80 90 100 110 120
TKQSLGKCPQ MHLTKHKIQY EREVKQGKTF PEFEREYLAI LSRFVNECNG QISVALQNLK

130 140 150 160 170 180
HTAEERMKIQ QVTEELDVLD VRIGLMGQEI DSLIRADEVS MGMLQSVKLQ ELISKRKEVA

190 200 210 220 230 240
KRVRNITENV GQSAQQKLQV CEVCGAYLSR LDTDRRLADH FLGKIHLGYV KMREDYDRLM

250 260
KNNRTTNASK TATTLPGRRF V


References and documentation are available.

Number of amino acids: 261 Molecular weight: 30194.76 Theoretical pI: 9.31
Amino acid composition: 
Ala (A) 12 4.6% Arg (R) 22 8.4% Asn (N) 9 3.4% Asp (D) 13 5.0% Cys (C) 6 2.3% Gln (Q) 19 7.3% Glu (E) 20 7.7% Gly (G) 15 5.7% His (H) 8 3.1% Ile (I) 11 4.2% Leu (L) 27 10.3% Lys (K) 21 8.0% Met (M) 10 3.8% Phe (F) 8 3.1% Pro (P) 6 2.3% Ser (S) 15 5.7% Thr (T) 14 5.4% Trp (W) 0 0.0% Tyr (Y) 8 3.1% Val (V) 17 6.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 33 Total number of positively charged residues (Arg + Lys): 43 Atomic composition: Carbon C 1311 Hydrogen H 2140 Nitrogen N 392 Oxygen O 393 Sulfur S 16 Formula: C1311H2140N392O393S16 Total number of atoms: 4252 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 12295 Abs 0.1% (=1 g/l) 0.407, assuming all pairs of Cys residues form cystines Ext. coefficient 11920 Abs 0.1% (=1 g/l) 0.395, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 53.71 This classifies the protein as unstable. Aliphatic index: 80.27 Grand average of hydropathicity (GRAVY): -0.637