ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MSTNTEIIKN SDLQSLINDK RRLINEIKDF NKSIKPLEFE SYQDYFLIKT FKKGISASGH 

        70         80         90        100        110        120 
VDIDSLRNKE YGIYYKKIKR NSTQEVGEPI PRNTSSSSSS TRSNSSADIS DTEYSGENTP 

       130        140        150        160        170        180 
TTTGAASRRR RTRSRAIQRE NSLPASLPSI SEANANNDDV TISEINGSEL PFPIPISEVE 

       190        200        210        220        230        240 
NIDIASDITE RDGIRRRSSR ISERDKRRSQ SRLGSEEDEE GDGHDGDEGE TKIQDLYESL 

       250        260        270        280        290        300 
VPKILESRRR SDWILPPKAR YTPEKQMRTK PSFKSIKINE LVGNKRIRSI LSRFEGGVAG 

       310 
IRKRDWDSTQ 

References and documentation are available.

Number of amino acids: 310

Molecular weight: 35194.98

Theoretical pI: 9.04

Amino acid composition: 
Ala (A)  11	  3.5%
Arg (R)  32	 10.3%
Asn (N)  18	  5.8%
Asp (D)  22	  7.1%
Cys (C)   0	  0.0%
Gln (Q)   8	  2.6%
Glu (E)  28	  9.0%
Gly (G)  17	  5.5%
His (H)   2	  0.6%
Ile (I)  32	 10.3%
Leu (L)  16	  5.2%
Lys (K)  22	  7.1%
Met (M)   2	  0.6%
Phe (F)   7	  2.3%
Pro (P)  14	  4.5%
Ser (S)  44	 14.2%
Thr (T)  18	  5.8%
Trp (W)   2	  0.6%
Tyr (Y)   8	  2.6%
Val (V)   7	  2.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 50
Total number of positively charged residues (Arg + Lys): 54

Atomic composition:

Carbon      C	      1507
Hydrogen    H	      2456
Nitrogen    N	       460
Oxygen      O	       507
Sulfur      S	         2

Formula: C1507H2456N460O507S2
Total number of atoms: 4932

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    22920
Abs 0.1% (=1 g/l)   0.651

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 72.92
This classifies the protein as unstable.



Aliphatic index: 70.48

Grand average of hydropathicity (GRAVY): -1.013